Patients satisfying the inclusion criteria will be divided into 2 groups based on closed envelope technique. Patients belonging to the interventional group will be considered as Group L and thoseserving as controls will be Group C. Baseline echocardiography, liver function tests, renal function tests, serum lipid profile, cTnI , ProBNP will be noted prior to surgery. Revascularisation will be done by a single surgeon and it usually takes 60 to 90 minutes for complete revascularisation (2 to 3 grafts) in our institute. Sixty two patients, scheduled to undergo elective OPCAB surgery, will be randomly assigned to the IL group (n = 31) or control (C) group (n = 31); the IL group will receive an infusion of 20% IL 2 ml/kg from the start of Left Internal Mammary Artery harvesting till the end of grafting over a period of 90 minutes, whereas the control group will receive an equivalent volume of normal saline. Hemodynamics will be continuously monitored during intralipid infusion. Serum levels of cTnI and NT ProBNP will be noted before surgery and at 6 h, 24 h, 48 h, and 72 h postoperatively. Also, intraoperative hemodynamic parameters, inotrope use, ventilatory hours, ICU stay, postoperative left ventricular ejection fraction, postoperative lipid profile, renal and hepatic function tests will be measured. Echocardiography, LFTs, RFTs will be monitored prior to surgery and also on POD1 and POD3.