Diabetes Mellitus is a Metabolic disorder. Characterised by chronic hyperglycaemia with disturbances of carbohydrate, fat & protein metabolism resulting from defects in insulin secretion, insulin action or both. Long term diabetes can causes consequences like brain damage,heart diseases,nephritic,neurotic disease , retinal diseases, amputation that is micro vascular and macro vascular. Diabetes can be correlated to Madhumeha in Ayurveda. Symtopms of Madhumeha like prabhut mutrata ,avil mutrata, pipasaaadhikya can be correlated with polyurea ,urine turbidity ,polydipsia in Diabetes Mellitus type 2.The Prevalence of Diabetes in India is 11.8% according to the National Diabetes and Diabetic Retinopathy Survey report released by the health and family welfare ministry. With increasing incidence of Diabetes Mellitus-II due to changed lifestyle & habits disease has been became as major health issues in society. Disease Progress with many complications leading to cause major illness hampering daily activities of patients. As well as drugs used for treatment also cause many complications. So there is need to aware about disease severity, side effects of modern medicine and modifications in lifestyle. There is need for effective, safe, potent, drug which controls hyperglycemia any adverse reaction and limit the signs symptoms related to Diabetes Mellitustype2. Hence, in the present study will be done on the effects of Kantak panchamula churna on lowering blood sugar level as drug is stated by Sushruta in 38 th chapter of Sushrut sutrasthana.