Knee osteoarthritis also known as degenerative joint disease, is typically the result of wear and tear of the articular cartilage. It may lead to muscle weakness, increased joint loading, alteration in the gait pattern  and increase the knee adduction movement. The objective of the study is to determine the impact of the Hamstring Active Release Technique (ART) program on range of motion in patients with grade 1 and 2 knee osteoarthritis. Active release technique is a manual therapy for the recovery of soft tissue function that involve the removal of adhesions, which can cause pain, stiffness, and muscle weakness. To determine the impact of the Hamstring Active Release Technique (ART) program on range of motion and the Isokinetic Hamstring to Quadriceps Strength Ratio in patients with Grade 1 And 2 Knee Osteoarthritis. On the basis of inclusion and exclusion criteria. Subjects will be randomly allocated into Group 1, Group 2 through computer based random allocation techniques. Group 1 will receive Active release technique with conventional physiotherapy treatment and Group 2 will receive only conventional physiotherapy treatment. Pre-test and post-test assessment will be done by Numerical Pain rating scale (NPRS), Goniometer to measure Active and Passive range of motion and hamstring and quadriceps strength ratio using Sphygmomanometer test. This research aligns with a patient-centered approach, and a deeper understanding of the musculoskeletal health, and the choice of additional physiotherapy treatment approaches.