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CTRI Number  CTRI/2025/04/084288 [Registered on: 07/04/2025] Trial Registered Prospectively
Last Modified On: 02/04/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Drug
Ayurveda 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   Use Of Marich Sharkara Churna in Vataj Kasa 
Scientific Title of Study   An Open Randomized Controlled Clinical Trial of Marich Sharkara Churna in Vataj Kasa 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Shubham Dilip Patil 
Designation  PG Scholar 
Affiliation  Hon Shri Annasaheb Dange Ayurved Medical College Post Graduate And Research Center 
Address  OPD No 1 Kayachikitsa OPD Ground Floor Dhanvantari Ayurved Hospital Ashta Tal Walwa Dist Sangli

Sangli
MAHARASHTRA
416301
India 
Phone  9975536478  
Fax    
Email  shubhampatil199714@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Smita Vitthal Lokhande 
Designation  Associate Professor 
Affiliation  Hon Shri Annasaheb Dange Ayurved Medical College Post Graduate And Research Center 
Address  Department Of Kayachikitsa 3rd Floor Hon Shri Annasaheb Dange Ayurved Medical College Post Graduate & Research Center Ashta Tal Walwa Dist Sangli

Sangli
MAHARASHTRA
416301
India 
Phone  8149556591  
Fax    
Email  yoshitpriya@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Smita Vitthal Lokhande 
Designation  Associate Professor 
Affiliation  Hon Shri Annasaheb Dange Ayurved Medical College Post Graduate And Research Center 
Address  Department Of Kayachikitsa 3rd Floor Hon Shri Annasaheb Dange Ayurved Medical College Post Graduate & Research Center Ashta Tal Walwa Dist Sangli

Sangli
MAHARASHTRA
416301
India 
Phone  8149556591  
Fax    
Email  yoshitpriya@gmail.com  
 
Source of Monetary or Material Support  
Hon Shri Annasaheb Dange Ayurved Medical College Post Graduate and Research Center Ashta tal walwa dist sangli maharashtra india 416301 
 
Primary Sponsor  
Name  Dr Shubham Dilip Patil 
Address  OPD No 1 Kayachikitsa OPD Ground Floor Dhanvantari Ayurved Hospital Ashta Tal Walwa Dist Sangli Maharashtra India 416301 
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Shubham Dilip Patil  Hon Shri Annasaheb Dange Ayurved Medical College Post Graduate And Research Center Ashta  OPD no 1 Kayachikitsa OPD Ground Floor Dhanvantari Ayurved Hospital Ashta Tal Walwa Sangli
Sangli
MAHARASHTRA 
9975536478

shubhampatil199714@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethical Committee Of Hon Shri Annasaheb Dange Ayurved Medical College And Post Graduate And Research Center Ashta Sangli  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition:J399||Disease of upper respiratory tract, unspecified. Ayurveda Condition: KASAH,  
 
Intervention / Comparator Agent  
snoIntervention/ComparatorTypeDrug-TypeProcedure NameDetails
1Intervention ArmDrugClassical(1) Medicine Name: Marich Sharkara Churna, Reference: Sushrut Samhita Uttartantra, Route: Oral, Dosage Form: Churna/ Powder, Dose: 1(g), Frequency: bd, Bhaishajya Kal: Adhobhakta, Duration: 7 Days, anupAna/sahapAna: Yes(details: Ghrut and Madhu), Additional Information: -
2Comparator ArmDrugClassical(1) Medicine Name: Vasabhavit Haridra Churna, Reference: Siddha Bheshaj Manimala, Route: Oral, Dosage Form: Churna/ Powder, Dose: 3(g), Frequency: bd, Bhaishajya Kal: Adhobhakta, Duration: 7 Days, anupAna/sahapAna: Yes(details: Dugdha Santanika), Additional Information: -
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  60.00 Year(s)
Gender  Both 
Details  1 Cases with confirmed diagnosis by signs symptoms of Vataj Kasa
2 Duration of illness not more than 1 week
3 Repeated attacks of Vataj Kasa
4 Patients of either sex with Age between 18 years to 60 years
5 Patients will be selected irrespective of age gender socioeconomic status 
 
ExclusionCriteria 
Details  1 Patient with co-morbidities like Diabetes Mellitus Ischemic Heart Diseases and other serious cardiovascular disorders
2 Pregnancy and Lactating Mothers
3 Known case of Tuberculosis Pneumonia Bronchial asthma Bronchial carcinoma occupational lung disease Allergic Bronchopulmonary Aspergillosis etc
4 Patients giving history of Hematemesis Hemoptysis during cough 
 
Method of Generating Random Sequence   Other 
Method of Concealment   Case Record Numbers 
Blinding/Masking   Open Label 
Primary Outcome  
Outcome  TimePoints 
Marich sharkara Churna Is Effective In the Management of Vataj Kasa  7 Days 
 
Secondary Outcome  
Outcome  TimePoints 
Vasabhavit Haridra Churna Is effective In the Management Of vataj kasa  7 Days 
 
Target Sample Size   Total Sample Size="72"
Sample Size from India="72" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 2/ Phase 3 
Date of First Enrollment (India)   01/05/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Open to Recruitment 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  
Environmental changes constantly impact the human body. Pollution and urbanization deteriorating the quality of life on Earth. The purity of the air we breathe, the water we drink, and the food we consume doesn’t always promote health; instead, it burdens the body’s immune system and overall health.
Kasa, a disease of pranvaha strotas, arises from an imbalance of the three doshas. The disturbed Pran vayu, along with Udan vayu aggravated, when combined with other doshas and is forcefully expelled with a coughing sound resembling a cracked bronze vessel, known as kasa. It represents the body’s attempt to eliminate excessive secretions, foreign matter, and other harmful substances from the Respiratory tract.
Vataj kasa is one of the most frequent complaints encountered in general practice every day. It is one among the types of Kasa, where Shuska Kasa is prominent symptom. Vataj kasa characterized by Lakshanas like Shushka kantha, vaktra, Shushka kasa with Shushka alpakapha, Swarbheda, Parshvashool, Shriashool, Urashool, Dourbalya as explained in Ayurvedic texts.
Prevalence of vataj kasa is 10%.  Cough is foremost and enduring symptom of respiratory illnesses, prompted by the stimulation of sensory nerves within the mucosa of the respiratory tract. This reflex can become acutely sensitized in various conditions, typically by exposure to irritants like dust, cigarette smoke, pollens, or shifts in climate and atmospheric conditions. Which are also explained as hetu of vataj kasa.
The Composition Marich sharkara churna explained as Kasahar in the Sushrut Samhita, Uttartantra  is selected for trial of present study. which helps to decrease the symptoms of kasa. Also, the Vasa bhavit haridra churna as stated in siddha bhaishajya manimala is used for control study.
 
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