BACKGROUND:

         Siddha system of medicine provides rejuvenate health care based on the principles of pancha Bootham. The Siddha medicines are broadly classified into 32 Internal medicines & 32 External medicines which plays a significant role in the treatment & management of various disease.Hypertension is one of the major public health problems around the globe and its prevalence is rapidly increasing among developing countries. It’s important to note  that increase in hypertension directly contribute on even more serious conditions like strokes, diabetes, heart diseases and renal impairment.Therefore management of  hypertension has become a biggest challenge in developing country like India. Hypertension, commonly known as high blood pressure defined with standard criteria as systolic BPgreater than or equal to 140 mmHg and diastolic BP greater than or equal to 90 mmHg. Prevalence of hypertension in India is at alarming level and is estimated to account for 10.8% of all the deaths in the country.Lack of awareness is one of the major factor leads to increased prevalence of  hypertension in India. Many people are not aware about their hypertension condition,even in some cases the reason for death remains elusive as most of the time person suffering from hypertension do not show any visible symptoms, remains normal and diagnosed only after appearance of cardio vascular disease or stroke.According to the global burden of diseases estimate 2015, hypertension is a most important cause of mortality. It is estimated that, 57% and 24% of stroke and coronary artery disease-related deaths respectively are due to hypertension.

            In Siddha, various botanical species and their preparations have proven to be advantageous in the management of cardiovascular ailments. Multiple pieces of data exist that demonstrate the efficacy of different Siddha medications in treating cardiovascular problems. The clinical trial indicates that marudham pattai is effective in treating congestive heart failure, chronic stable angina, and hypertension. The marudham pattai tree and its components, such as arjunolic acid, exhibit a cardioprotective effect in rats by virtue of their antioxidant activity . The alcoholic extract derived from the bulb of Allium ascalonicum demonstrates a favourable impact on the proteolytic and hypocholesterolemic activity in rabbits . The rhizome of Curcuma longa Linn, also known as turmeric, and its active compound curcumin, have demonstrated a hypolipidemic impact, anti  atherosclerotic activity, and antithrombotic effect. Recent research have shown that natural components effectively inhibit, regulate, and impede key factors associated with cardiovascular disease, such as oxidative stress and inflammatory mediators. Medicinal herbs have been beneficial in treating individuals with congestive heart failure, systolic hypertension, angina pectoris, atherosclerosis, cerebral insufficiency, and venous insufficiency..

    OBJECTIVE:

PRIMARY OBJECTIVE:

To evaluate the clinical effectiveness of siddha formulation  Seedhobalathi Chooranam in the management of Essential hypertension (according to Joint Nationl Committee 8 guideliness) among the patients attending Ayothidoss Pandithar Hospital, National Institute of Siddha.

SECONDARY OBJECTIVE:

The Quality of life in patients with hypertension through SF-36             Questionnaire will be assessed before and after treatment.

STUDY DESIGN:

This is an interventional study of Non randomized sampling which will be carried out for 1 year in patients with Essential hypertension reporting at Ayothidoss Pandithar Hospital, National Institute of Siddha, Chennai – 600 047 with 30 participants as sample size. Participants with age 18 to 59 years of both sex, Participants with Stage 1 Hypertension according to JNC 8 guidelines will be included in this study. Participants with liver diseases, kidney disease, hematopoietic disease, malignant tumor, cardiac diseases,  cerebrovascular diseases, white collar hypertension, Pregnant women. Patient who are taking anti-hypertensive medication will been excluded in this study.

OUTCOME: 

PRIMARY OUTCOME:

The changes in  systolic and diastolic blood pressure will be assessed  before and after treatment according to JNC 8  guidelines.

 SECONDARY OUTCOME:

The quality of life in patients with hypertension through SF-36 questionnaire will be assessed before and after treatment.

RESULTS AND DISCUSSION:

The results will be statistically analyzed and reported.

KEYWORDS: Kuruthi azhal noi, Essential Hypertension, Seedhobalathi chooranam, Siddha Medicine.