FULL DETAILS (Read-only)  -> Click Here to Create PDF for Current Dataset of Trial
CTRI Number  CTRI/2025/04/083854 [Registered on: 02/04/2025] Trial Registered Prospectively
Last Modified On: 19/08/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Homeopathy 
Study Design  Single Arm Study 
Public Title of Study   TO STUDY THE ROLE OF MIASMS IN CASES OF CHRONIC TONSILLITIS AND ITS HOMOEOPATHIC MANAGEMENT 
Scientific Title of Study   MIASMATIC INTERPREATATION OF CHRONIC TONSILITIS AND IT’S HOMOEOPATHIC MANAGEMENT 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Rashmi Vaghela 
Designation  PG Scholer 
Affiliation  Rajkot Homoeopathic Medical College 
Address  Department of Organon of Medicine and Homoeopathic Philosophy, Rajkot Homoeopathic Medical College, behind jainath complex, makkam chowk, Rajkot

Rajkot
GUJARAT
360002
India 
Phone  9173179249  
Fax    
Email  rashamivaghela95@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Mital N Kacha  
Designation  Assistant Professor 
Affiliation  Rajkot Homoeopathic Medical College 
Address  Department of Organon of Medicine and Homoeopathic Philosophy, Rajkot Homoeopathic Medical College, behind jainath complex, makkam chowk, Rajkot

Rajkot
GUJARAT
360002
India 
Phone  9099144019  
Fax    
Email  dr.mitalkacha@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Rashmi Vaghela 
Designation  PG Scholer 
Affiliation  Rajkot Homoeopathic Medical College 
Address  Department of Organon of Medicine and Homoeopathic Philosophy, Rajkot Homoeopathic Medical College, behind jainath complex, makkam chowk, Rajkot

Rajkot
GUJARAT
360002
India 
Phone  9173179249  
Fax    
Email  rashamivaghela95@gmail.com  
 
Source of Monetary or Material Support  
Rajkot Homoeopathic Medical Collage,Parul university 
 
Primary Sponsor  
Name  Rajkot Homoeopathic Medical Collage,Parul university 
Address  Department of Organon of Medicine and Homoeopathic Philosophy, Rajkot Homoeopathic Medical College, behind jainath complex, makkam chowk, Rajkot Gujrat 360002 India 
Type of Sponsor  Private medical college 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Rashmi Vaghela  RAJKOT HOMOEOPATHIC MEDICAL COLLAG  Department of Organon of Medicine and Homoeopathic Philosophy,Rajkot Homoeopathic Medical College,behind Jainath Complex, Makkam chowk, Rajkot, Gujrat 360002 India
Rajkot
GUJARAT 
9173179249

rashamivaghela95@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee for Human Research - Rajkot Homoeopathic Medical College (RHMC), Parul University, Gujara  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: J350||Chronic tonsillitis and adenoiditis,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  individualized homoeopathic medicine  Individualized homoeopathic medicine selected on basis of underlying miasm by repertorial aspect and mangement of case. Mode of Administration: Oral(sublingual) Selection of potency, dose and repetition: individualised medicine will be presecribed in 30, 200, 1 M potency. selection of dosage, potency and repitation will be according to susceptibility of patient and principles of organon of medicine 
Comparator Agent  not applicable  not applicable 
 
Inclusion Criteria  
Age From  5.00 Year(s)
Age To  45.00 Year(s)
Gender  Both 
Details  All socio-economic class view considered. 
 
ExclusionCriteria 
Details  Age below 5 and more than 45
Pregnant and lactating women.
Chronic tonsillitis cases with major complications
Patients on prolonged immunosuppression and antibiotic therapy.
Cases with irregular follow ups & patients who had not followed personal hygiene advises and auxiliary measures as advised by the physician.
Cases of chronic disease with irreversible pathological changes.
 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Case Record Numbers 
Blinding/Masking   Participant Blinded 
Primary Outcome  
Outcome  TimePoints 
there will be some improvement after prescribing homoeopathic medicines  it will be assessed every 2 weeks and will be tried to achieve maximum by 9 months  
 
Secondary Outcome  
Outcome  TimePoints 
Significant Improvement- sense of well being with no complaints or relapse of the
symptoms.
Moderate Improvement- patient relieved from presenting complaints in frequency & intensity.
Status quo- when there is neither increase nor decrease in the intensity of symptoms.
 
This may be also achieved within the time frame of primary outcome that is within 9 months 
 
Target Sample Size   Total Sample Size="40"
Sample Size from India="40" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   Phase 2 
Date of First Enrollment (India)   05/04/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="9"
Days="0" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary
Modification(s)  

Recurrent tonsillitis is described as when an individual suffers from several attacks of tonsillitis per year. Chronic and recurrent tonsillitis both cause repeated occurrences of inflamed tonsils which have a significant impact on a patient’s quality of life. Numerous children suffer from recurrent tonsillitis and sore throats, and these illnesses become part of their life. Antimicrobials can provide temporary relief, but in many cases tonsilitis recurs. The cause of such recurrent infections have been identified as microorganisms which often create biofilms and a repository of infection in the wet and warm folds of the tonsils. Chronic inflammatory changes in the tonsils are usually the result of recurrent acute infections treated inadequately. Recurrent infections lead to development if minute abscesses within the lymphoid follicles. These become walled off by fibrous tissue and surrounded by inflammatory cells. 

Homoeopathy is a system of medicine that has scope in chronic or recurrent tonsilitis because allopathy has nothing to offer other than tonsillectomy. Treatment option of chronic or recurrent tonsilitis include the conservative treatment consists of attention to general health, diet, treatment of coexistent infection of teeth, nose & sinuses. Tonsillectomy is indicated when tonsils interfere with speech, deglutination and respiration or cause recurrent attacks. As Hahnemann described it, a miasm defined as the fundamental cause of an erroneous or diseased state of the. Chronic conditions are caused by chronic miasms, just as acute conditions are caused by acute miasms. Miasms cause a complete dynamic and physical change to the interior of the whole man...his whole being is altered. It is only after this complete change has occurred that symptoms of the disease change have occurred that the disease or illness are demonstrated. Chronic diseases slowly progress and symptoms result over the course of a lifetime, due to an inadequate constitutional response to a miasm. With respect to acute disease or illness,there is a rapid onset of symptoms progressing towards a crisis which ends in recovery or death without treatment. For example, cancer is typically a chronic disease that progresses slowly over the years whereas the flu is an acute disease that progress swiftly over a few days. In both conditions the entire body has to be compromised or changed by the miasm before the symptoms are demonstrated by the patients. So, in case chronic tonsilitis that is result from recurrent attack of acute tonsilitis or infection of the tonsils that lasts longer than a week or two, there is underlying chronic miasms is present. So, in homoeopathy in such chronic conditions or disease or recurrent disease on the basis of underlying prominent miasm of patient we give the simillimum & anti-miasmatic medicines to the patient. By this way we can treat the person as a whole & remove the disease from its root. We can also prevent the disease by preservative measures. In case of chronic diseases we can also prevent surgical measures or recurrency by giving proper homoeopathic medicine on basis of miasms. So, our purpose of study of miasmatic interpretation of chronic tonsillitis is to prevent tonsillectomy & to prevent recurrence of tonsillitis and to remove the disease from its root. Homoeopathic management of chronic tonsillitis include both preventive and medicinal view. Because prevention is always better than cure. We can prevent the recurrent tonsillitis by good oral hygiene and other ways. And by giving simimllimum homoeopathic medicines also cure the chronic tonsillitis from root without tonsillectomy and no recurrence occur.

v RESEARCH QUESTION: -

How is miasms useful in the management of Chronic Tonsillitis or Recurrent Tonsillitis.

  HYPOTHESIS: -

1.     Null Hypothesis —

There will be no improvement after prescribing Homoeopathic Medicine in case of chronic tonsillitis.

2.     Alternate Hypothesis —

There will be significant improvement in symptoms after prescribing Homoeopathic medicine in case of chronic tonsillitis.

 

 
Close