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CTRI Number  CTRI/2025/09/094965 [Registered on: 17/09/2025] Trial Registered Prospectively
Last Modified On: 16/09/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Yoga & Naturopathy 
Study Design  Randomized, Parallel Group, Multiple Arm Trial 
Public Title of Study   A study to see if daily practice of simple breathing techniques (Bhramari, Om Chanting and Nadi Shodhana) can improve hand–eye coordination and finger skills in medical students. 
Scientific Title of Study   Effect of Om Chanting, Bhramari Pranayama, Nadi Shodhana Pranayama on Tweezer Dexterity Score amongst undergraduate students at Government Medical College 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Sai Krishna Ambidi 
Designation  Junior Resident 3rd Year Post Graduate  
Affiliation  Goa Medical College 
Address  Department of Physiology Goa Medical College Bambolim

North Goa
GOA
403202
India 
Phone  8790797937  
Fax    
Email  saikrrish020489@gmail.com  
 
Details of Contact Person
Scientific Query  
Name  Dr Sai Krishna Ambidi 
Designation  Post Graduate, Department of Physiology 
Affiliation  Goa Medical College 
Address  Department of Physiology Goa Medical College Bambolim

North Goa
GOA
403202
India 
Phone  8790797937  
Fax    
Email  saikrrish020489@gmail.com  
 
Details of Contact Person
Public Query  
Name  Dr Sai Krishna Ambidi 
Designation  Junior Resident 3rd Year Post Graduate  
Affiliation  Goa Medical College 
Address  Department of Physiology Goa Medical College Bambolim

North Goa
GOA
403202
India 
Phone  8790797937  
Fax    
Email  saikrrish020489@gmail.com  
 
Source of Monetary or Material Support  
NIL 
 
Primary Sponsor  
Name  Dr Sai Krishna Ambidi 
Address  Deparment of Physiology Goa Medical College Bambolim 
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
DrSai Krishna Ambidi  Goa Medical College  Department of Physiology, 4th floor, Super speciality Block, Bambolim, North Goa, Goa - 403202
North Goa
GOA 		 8790797937

saikrrish020489@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
GOA MEDICAL COLLEGE INSTITUITIONAL ETHICS COMMITTEE  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  Normal 
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  Active comparator – Bhramari Pranayama Active comparator – Om Chanting Active comparator – Nadi Shodhana Pranayama  ogic breathing exercise (humming bee breath), 10 minutes daily for 7 consecutive days. Compared with Om Chanting and Nadi Shodhana Pranayama. Meditative chanting exercise, 2 minutes daily for 7 consecutive days. Compared with Bhramari and Nadi Shodhana Pranayama. Yogic breathing exercise (alternate nostril breathing), 10 minutes daily for 7 consecutive days. Compared with Bhramari and Om Chanting. 
Intervention  Group A: Bhramari pranayama Group B: Om chanting Group C: Nadi Shodhana pranayama  Type: Yogic breathing exercise (humming bee breath) Dose/Duration: 10 minutes daily × 7 consecutive days Mode: Performed in seated posture, under supervision in Department of Physiology Type: Meditative chanting exercise Dose/Duration: 2 minutes daily × 7 consecutive days Mode: Performed in seated posture, under supervision Type: Yogic breathing exercise (alternate nostril breathing) Dose/Duration: 10 minutes daily × 7 consecutive days Mode: Performed in seated posture, under supervision 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  25.00 Year(s)
Gender  Both 
Details  Undergraduate and postgraduate medical students of age group (18 to 30 years old) who should be free from any acute and chronic diseases.
Participants who are willing to participate.
Participants with no prior training in Pranayama or Meditation.
No Vision impairment and Hand Function 
 
ExclusionCriteria 
Details  Participants who are not willing to participate in the study.
Participants who are already practicing pranayama on regular basis.
Participants who have a history of any neurological or musculoskeletal disorders.
Participants who are using stimulants or sedatives.
Participants with acute illness or recent surgery.
Participants with High stress periods or Sleep Deprivation.
Participants with psychiatric or Psychological conditions. 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
Change in Tweezer Dexterity Score (number of pins placed in 4 min) from Day 1 (baseline) to Day 7  Change in Tweezer Dexterity Score (number of pins placed in 4 min) from Day 1 (baseline) to Day 7 
 
Secondary Outcome  
Outcome  TimePoints 
Gender-wise differences; adherence; adverse events  Gender-wise comparison of post-intervention Tweezer Dexterity Score at Day 7.
Participant adherence (% of sessions completed) recorded over 7 days.
Incidence & description of any adverse events during the 7-day intervention. 
 
Target Sample Size   Total Sample Size="150"
Sample Size from India="150" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   27/09/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="3"
Days="0" 
Recruitment Status of Trial (Global)   Completed 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

This study aims to evaluate the effect of three different pranayama techniques — Bhramari Pranayama, Om Chanting, and Nadi Shodhana Pranayama — on fine motor coordination among undergraduate medical students. Fine motor skills are essential in clinical practice, and yoga-based breathing practices have been shown to improve autonomic regulation, attention, and neuromuscular control.

A total of 150 healthy volunteers (75 males and 75 females) aged 18–24 years will be randomly allocated into three groups of 50 each. Group A will practice Bhramari Pranayama (10 minutes daily), Group B will practice Om Chanting (10 minutes daily), and Group C will practice Nadi Shodhana Pranayama (10 minutes daily), for 7 consecutive days.

The primary outcome will be the change in Tweezer Dexterity Score (TDS), measured as the number of cylindrical pins placed within 4 minutes, recorded at baseline (Day 1) and post-intervention (Day 7). Within-group comparisons and between-group analyses will be performed to assess improvement in dexterity. Gender differences will also be explored.

The findings are expected to identify which pranayama technique is most effective in enhancing fine motor coordination, with potential implications for improving psychomotor readiness in medical education.

 
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