FULL DETAILS (Read-only)  -> Click Here to Create PDF for Current Dataset of Trial
CTRI Number  CTRI/2025/03/082837 [Registered on: 19/03/2025] Trial Registered Prospectively
Last Modified On: 19/03/2025
Post Graduate Thesis  Yes 
Type of Trial  Observational 
Type of Study   Cross Sectional Study 
Study Design  Other 
Public Title of Study   how people with Parkinson’s disease can sense the position and movement of their legs (proprioception) and how this affects their ability to move and perform daily activities. 
Scientific Title of Study   An Analysis Of Single And Multijoint Proprioception Of Lower Limb And Functional Mobility Among Patients With Parkinsons Disease 
Trial Acronym  Nil 
Secondary IDs if Any  
Secondary ID  Identifier 
nil  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Sravani P N 
Designation  MPT Neurosciences 
Affiliation  Sri Ramachandra Institute of Higher Education and Research 
Address  Sri Ramachandra Institute of Higher Education and Research Faculty of Physiotherapy Room 2.2No 1 Ramachandra Nagar Chennai,TAMIL NADU 600116 India

Chennai
TAMIL NADU
600116
India 
Phone  8056242474  
Fax    
Email  sravanipn2001@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Radhika C M 
Designation  MPT NEUROSCIENCES 
Affiliation  Sri Ramachandra Institute of Higher Education and Research 
Address  Sri Ramachandra Institute of Higher Education and Research Faculty of Physiotherapy 2nd Floor No 1 Ramachandra Nagar Chennai Tamilnadu 600116 India

Chennai
TAMIL NADU
600116
India 
Phone  9841376961  
Fax    
Email  radhikacm@sriramachandra.edu.in  
 
Details of Contact Person
Public Query
 
Name  Radhika C M 
Designation  MPT NEUROSCIENCES 
Affiliation  Sri Ramachandra Institute of Higher Education and Research 
Address  Sri Ramachandra Institute of Higher Education and Research Faculty of Physiotherapy 2nd Floor No 1 Ramachandra Nagar Chennai Tamilnadu 600116 India

Chennai
TAMIL NADU
600116
India 
Phone  9841376961  
Fax    
Email  radhikacm@sriramachandra.edu.in  
 
Source of Monetary or Material Support  
Department of Neurology G Block Sri Ramachandra Institute of Higher Education and Research. No 1 Ramachandra Nagar Sri Ramachandra Nagar Chennai Tamilnadu India 
 
Primary Sponsor  
Name  Sravani P N 
Address  Sri Ramachandra Institute of Higher Education and Research .No 1 Ramachandra Nagar Sri Ramachandra Nagar Chennai Tamilnadu India 
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Radhika C M  Department of Neurology Sri Ramachandra Institute of Higher Education and Research  Sri Ramachandra Institute of Higher Education and Research, Faculty of Physiotherapy No 1 Ramachandra Nagar Chennai TAMIL NADU 600116 India
Chennai
TAMIL NADU 
9841376961

radhikacm@sriramachandra.edu.in 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Sri Ramachandra Ethics Committee For Students Projects  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: G20||Parkinsons disease,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Nil  Nil 
Comparator Agent  Nil  Nil 
 
Inclusion Criteria  
Age From  40.00 Year(s)
Age To  70.00 Year(s)
Gender  Both 
Details  Patient diagnosed with Parkinsons disease
Adults with mild to moderate parkinsons disease
If they able to walk independently with or without aid 
 
ExclusionCriteria 
Details  1.Individuals with cognitive impairment will be excluded from the study since they have difficulty understanding the instructions given.
2.Patients with early-onset PD and late stages of PD
3.A history of other neurological disease(s), or a history of severe ankle injury
 
 
Method of Generating Random Sequence   Other 
Method of Concealment   Other 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
1.JOINT REPOSITION TEST FOR HIP AND KNEE JOINT
2.TARGET POINT
 
One Time (1 day) 
 
Secondary Outcome  
Outcome  TimePoints 
TIMED UP AND GO TEST

 
One Time (1 day) 
 
Target Sample Size   Total Sample Size="30"
Sample Size from India="30" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   30/03/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="0"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

Parkinson’s is the second most common neurodegenerative disease. Parkinson’s disease is generally characterized by rigidity, tremor, bradykinesia, stooped posture, freezing of gait. Recent reports confirm the presence of proprioception deficit in patients with Parkinson’s disease.  Increased neuronal responses and noise within the basal ganglia lead to reduced joint specificity in proprioceptive integration, impairing accurate movement and coordination. This disruption impairs the brain’s capacity to accurately integrate sensory signals, causing diminished awareness of limb and trunk positions, particularly affecting kinesthesia (the sense of movement). As the disease progresses, these proprioceptive disturbances worsen, contributing to increasingly impaired movement coordination, greater challenges in motor control . Most of the studies are done proprioception in a single joint rather than using the multi-joint. where, Single-joint proprioception tests assess sensory feedback from specific joints but may not capture the broader impact on overall limb function. Whole-limb assessments offer a more comprehensive evaluation by considering how proprioceptive deficits affect the coordination and execution of movements involving multiple joints and muscles. This approach provides a better understanding of how proprioceptive impairments influence functional activities. Therefore, we could like to test single joint and multi-joint proprioception of lower limb in patients with Parkinson’s disease and to assess the presence of variation and its impact on functional mobility like gait patients with Parkinson’s.

 
Close