Generalized Anxiety Disorder (GAD), a prevalent mental health condition characterized by excessive worry and anxiety, can significantly impact daily functioning and quality of life if left untreated. While pharmacological interventions exist, Ayurveda offers alternative and complementary therapies with potential efficacy and fewer side effects. The concept of "Vishada," as described in the Shreemad Bhagavad Gita, particularly in the Arjuna Vishada Yoga, aligns with anxiety symptoms such as trembling, sweating, dry mouth, body shaking, goosebumps, burning sensations, apprehension, and fear of future events. Acharya Sushruta classified "Vishada" as a "Manasa roga" (mental disorder) in the Sushruta Samhita, with Dalhan further explaining it as a state of despair due to fear of failure. Similarly, Acharya Charaka examined Vishada in "Viman Sthan" and categorized it as a "Nanatamaj Vataj Vikara." This study aims to compare the efficacy of Ashtamangala Ghrita and Brahmi Ghrita in managing Generalized Anxiety Disorder (Vishada). The objectives include assessing their impact on Hamilton’s Anxiety Rating Scale, Pittsburgh Sleep Quality Index (PSQI), and serum cortisol levels, along with their effects on symptoms of Vishada and GAD. The null hypothesis (H0) states no difference in efficacy between the two formulations, whereas the alternative hypothesis (H1) suggests a difference. This Phase 2, single-center, randomized, double-blind, comparative clinical study will involve 60 patients over 28 days (4 weeks). Statistical analysis will include Mean, Standard Deviation, and Standard Error (SE), with intra-group assessment using the Wilcoxon matched-pairs signed ranks test for non-parametric data and the paired t-test for parametric data. Inter-group comparisons will utilize the Mann-Whitney test for non-parametric variables and the unpaired t-test for parametric variables.