| CTRI Number |
CTRI/2026/03/106815 [Registered on: 24/03/2026] Trial Registered Prospectively |
| Last Modified On: |
23/03/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Interventional |
|
Type of Study
|
Yoga & Naturopathy |
| Study Design |
Other |
|
Public Title of Study
|
Yoga Therapy for Hypothyroidism- Enhancing Health Through Mind-Body Practices |
|
Scientific Title of Study
|
Effect of Yoga Therapy on Autonomic Variables, Clinical Signs, and Thyroid Function in Hypothyroidism:
A Match-controlled Trial
|
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr Karthik P Hongal |
| Designation |
MD Scholar Clinical Yoga |
| Affiliation |
Shri Dharmasthala Manjunatheshwara College of Naturopathy and Yogic Sciences, Ujire. |
| Address |
College road, Near Siddhavana Bustand,
Dakshina Kannada.
Saraswathpur, Near Venkateshwara temple, Reddy bank, Dharwad - 580002
Dakshina Kannada
KARNATAKA
574240
India |
| Phone |
9902979473 |
| Fax |
|
| Email |
drkarthikphongal@gmail.com |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr Shivaprasad Shetty |
| Designation |
Dean & Professor |
| Affiliation |
Shri Dharmasthala Manjunatheshwara College of Naturopathy and Yogic Sciences, Ujire. |
| Address |
Department of Yoga Therapeutics, SDM College Of Naturopathy And Yogic Sciences Ujire, Belthangady Taluk, Dakshina Kannada Karnataka India.
Dakshina Kannada
KARNATAKA
574240
India |
| Phone |
9902979473 |
| Fax |
|
| Email |
drkarthikphongal@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr Karthik P Hongal |
| Designation |
MD Scholar Clinical Yoga |
| Affiliation |
Shri Dharmasthala Manjunatheshwara College of Naturopathy and Yogic Sciences, Ujire. |
| Address |
College road, Near Siddhavana Bustand,
Dakshina Kannada.
Saraswathpur, Near Venkateshwara temple, Reddy bank, Dharwad - 580002
KARNATAKA
574240
India |
| Phone |
9902979473 |
| Fax |
|
| Email |
drkarthikphongal@gmail.com |
|
|
Source of Monetary or Material Support
|
| SHRI DHARMASTHALA MANJUNATHESWARA YOGA AND NATURE CURE HOSPITAL SHANTIVANA DHARMASTHALA DAKSHINA KANNADA KARNATAKA INDIA 574216. |
|
|
Primary Sponsor
|
| Name |
DR KARTHIK P HONGAL |
| Address |
SDM College of Naturopathy and Yogic Sciences Ujire Belthangady Taluk Dakshina Kannada, Karnataka, India - 574240 |
| Type of Sponsor |
Other [SELF ] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Karthik P Hongal |
Centre of Excellence |
Shri Dharmasthala Manjunateshwara Yoga And Nature Cure Hospital Shantivana
Dharmasthala, Dakshina Kannada, Karnataka, India - 574216
Dakshina Kannada
KARNATAKA |
9902979473
hongalkartik4@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| SHRI DHARMASTHALA MANJUNATHESWARA COLLEGE OF NATUROPATHY AND YOGIC SCIENCES INSTITUTIONAL ETHICS COMMITTEE |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: E038||Other specified hypothyroidism, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
INTEGRATIVE APPROACH OF YOGA |
The treatment group will receive a 3-month yoga intervention, starting with 10 days of in-person training followed by tele-yoga sessions for the remaining duration. Yoga will be practiced for 60 minutes daily, 6 days a week, with weekly follow-up calls to ensure compliance.
Each session includes an opening prayer, joint loosening, and warm-up exercises. This is followed by breathing practices, Surya Namaskar, and a series of standing, sitting, prone, and supine asanas. Key practices include Vrikshasana, Trikonasana, Shashankasana, Bhujangasana, Sarvangasana, and Setubandhasana.
Pranayama techniques such as Kapalbhati, Bhastrika, Nadishuddhi, and Bhramari are also included. Sessions conclude with relaxation to promote mental calmness. |
| Comparator Agent |
TREATMENT AS USUAL |
CONTROL GROUP WONT RECEIVE ANY INTERVENTION AND CONTINUE STANDARD TREATMENT AS USUALLY |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
45.00 Year(s) |
| Gender |
Both |
| Details |
Subjects who are diagnosed with hypothyroidism disorder
Subjects who are keen to participate in this program
Subjects can follow the treatment instructions and respond to the survey questions in English to a satisfactory level
Under hypothyroidism medicines for 6months to less than 5 years |
|
| ExclusionCriteria |
| Details |
Psychotic disorder, Coronary artery disease, DVT, hypertension with beta blockers
Pregnant and breast feeding women
If undergone any surgery in last 6months |
|
|
Method of Generating Random Sequence
|
Other |
|
Method of Concealment
|
Other |
|
Blinding/Masking
|
Participant Blinded |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Thyroid Function Test : T3, T4, TSH |
Thyroid Function Test : T3, T4, TSH |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Zulewski’s Clinical Signs Questionnaire |
3 and 5 |
|
|
Target Sample Size
|
Total Sample Size="60"
Sample Size from India="60"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
10/06/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="0"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
The study titled Effect of Yoga Therapy on Autonomic Variables Clinical Signs and Thyroid Function in Hypothyroidism A Matched Controlled Trial by Dr Karthik P Hongal aims to evaluate the impact of yoga therapy on clinical signs autonomic variables and thyroid hormone levels in individuals with hypothyroidism This matched controlled trial involves 60 participants 30 in the treatment group and 30 in the control group aged between 18 to 45 years who have been diagnosed with hypothyroidism and are on thyroid medication for 6 months to 5 years The treatment group will undergo a structured yoga program for 3 months consisting of daily 60 minute sessions six days a week beginning with 10 days of in person training followed by tele-yoga sessions The yoga protocol includes loosening exercises a variety of asanas postures pranayama breathing techniques and relaxation methods aimed at stimulating thyroid function and balancing the autonomic nervous system The control group will continue their normal daily activities Clinical effectiveness will be measured using thyroid function tests T3 T4 TSH and Zulewskis Clinical Signs Questionnaire before and after the intervention The study expects to demonstrate that yoga therapy can lead to improvements in thyroid hormone levels and clinical symptoms offering a beneficial complementary approach to managing hypothyroidism |