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CTRI Number  CTRI/2025/04/085956 [Registered on: 29/04/2025] Trial Registered Prospectively
Last Modified On: 07/05/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Homeopathy 
Study Design  Single Arm Study 
Public Title of Study   Utility of Homoeopathic medicine in primary dysmenorrhoe  
Scientific Title of Study   Utility Of Homoeopathic Medical Repertory By Dr Robin Murphy In Management Of Primary Dysmenorrhoea  
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Soham Bhatt  
Designation  Pg scholar  
Affiliation  Rajkot Homoeopathic Medical College 
Address  Department of Case Taking and Repertory,Rajkot Homeopathic Medical College,Behind jainath complex,makkam chowk,Rajkot
Department of Case Taking and Repertory, Rajkot Homoeopathic Medical College, Behind jainath complex , makkam chowk , Rajkot
Rajkot
GUJARAT
360002
India 
Phone  9824816698  
Fax    
Email  sohambhatt1606@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Madhuri Udmale  
Designation  Assistant Professor  
Affiliation  Rajkot Homeopathic Medical College  
Address  Department of Case Taking and Repertory Rajkot Homeopathic Medical College,Behind jainath complex,makkam chowk,Rajkot

Rajkot
GUJARAT
360002
India 
Phone  9423465288  
Fax    
Email  madhuri.udmale31606@paruluniversity.ac.in  
 
Details of Contact Person
Public Query
 
Name  Dr Madhuri Udmale  
Designation  Assistant Professor  
Affiliation  Rajkot Homeopathic Medical College  
Address  Department of Case Taking and Repertory Rajkot Homeopathic Medical College,Behind jainath complex,makkam chowk,Rajkot

Rajkot
GUJARAT
360002
India 
Phone  9423465288  
Fax    
Email  madhuri.udmale31606@paruluniversity.ac.in  
 
Source of Monetary or Material Support  
Rajkot Homeopathic Medical College, Rajkot, Gujarat, India,360002 
 
Primary Sponsor  
Name  Rajkot Homeopathic Medical College  
Address  Rajkot Homeopathic Medical College,behind jainath complex,makkam chowk, Rajkot  
Type of Sponsor  Private medical college 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Soham Bhatt   Rajkot Homeopathic Medical College   Department of Case Taking and Repertory, Rajkot Homeopathic Medical College,behind jainath complex,makkam chowk, Rajkot,Gujarat
Rajkot
GUJARAT 
9824816698

sohambhatt1606@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Comittee For Human Research Rajkot Homoeopathic Medical College (RHMC) Parul University, Gujarat   Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: N944||Primary dysmenorrhea,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Homoeopathic medicines   Homoeopathic medicine will be prescribed mode of administration: oral (sublingual) selection of potency: 6,30,200,1M potency selection of potency and dosage: potency and repetition will be according to susceptibility of patient and principle of organon of medicine and will be done every month after follow up till 6 months 
Comparator Agent  Nil   Nil 
 
Inclusion Criteria  
Age From  10.00 Year(s)
Age To  19.00 Year(s)
Gender  Female 
Details  nulliparous females.
females having no pelvic pathology.
age group since menarche to 19 years of age.
females having regular menstrual cycle  
 
ExclusionCriteria 
Details  females having any pelvic pathology.
case of secondary dysmenorrhoea are to be excluded.
females above age of 19 years are to be excluded.
patients on OC pills or any other mode of treatment  
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Case Record Numbers 
Blinding/Masking   Participant Blinded 
Primary Outcome  
Outcome  TimePoints 
To ascertain the role of Homoeopathic Medical Repertory by Dr. Robin Murphy in cases of primary dysmenorrhoea.To ascertain the rubrics which are accessible in the case of primary dysmenorrhoea from Homoeopathic Medical Repertory by Dr. Robin Murphy  There will be some improvement after prescribing homoeopathic medicine which will be assessed at 4 weeks 
 
Secondary Outcome  
Outcome  TimePoints 
Significant outcome: patient with sense of well being with decrease in score between 1-4.Moderate improvement:patient wity sense of well being & decrease in score between 5-7.
No improvement or status quo: there is no considerable change observed in complaints & no decrease in score even after administration of
medicine.
 
There will be some improvement
after prescribing homoeopathic
medicine after 9 months 
 
Target Sample Size   Total Sample Size="40"
Sample Size from India="40" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   10/05/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="0"
Days="9" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary
Modification(s)  
Normally life stage of typical women is divided into infancy, puberty(adolescence), sexual maturation (reproductive age), climacteric period and post climacteric period (elderly).Puberty being developmental period where hormonal, psychological and physical change occurs simultaneously; menarche being the first menstrual period in females that typically occurs between the ages of 10 -16 years with the average age
of onset being 12.4 years.Primary dysmenorrhoea is a common complaint among both young and adult females. The onset of primary dysmenorrhoea predominantly occurs during
adolescence, usually within 6 to 24 months after menarche.
Primary dysmenorrhoea is defined as pain during menstrual cycle in the absence of any other recognisable cause and it is the most common cause of pelvic pain. The impact of primary dysmenorrhoea ranges from 45% - 95% in females of reproductive age group worldwide where 2%-29% females experience severe pain and a greater prevalence about 70%- 90% is generally reported in younger females.Primary dysmenorrhoea negatively affects females’ quality of life and
interferes with daily activities. The pathophysiology of primary dysmenorrhoea is likely a result of the cyclooxygenase pathway that increase prostanoids particularly prostaglandins. The high level of prostaglandins causes uterine contraction that restrict the blood flow and leads to the production of anaerobic metabolites that stimulates pain receptors.
Females with the typical history of primary dysmenorrhoea starts with the empirical treatment that includes pain relieving medications, anti-inflammatory medications, rarely oral combined contraceptive pills, heat application (hot water
bag), and regular exercise.Primary dysmenorrhoea is not only a physical issue but it’s a psychosocial issue affecting the life of females. Psychosocial issue in the sense of various orthodox
thoughts, beliefs that are followed in the society, their impact on an immature teenager girl makes her more non communicable, antisocial, emotionally vulnerable, and also affects her intellectual skills and abilities.The empirical method of taking medications like pain killers, antiinflammatory or oral combined contraceptive pills have pros and cons, if we focus
on the cons they have a bad effect on the individual in the form of constipation, stomach discomfort, bleeding problem, abnormal weight gain, hepatotoxicity, body swelling etc…
According to WHO the definition of health is “a complete state of physical, mental and social well-being and not merely the absence of disease.” Homoeopathy is a scientific and effective system of holistic healing having a concept of like cures like. Based on the principle that substance that cause symptoms in the healthy individual can alleviate similar symptoms in a sick individual. Conventional system works only on the particular part of the body and not on whole body but homoeopathy considers the whole person that is mind, body, emotion
and spirit.
 
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