Hypothyroidism is a prevalent endocrine disorder characterized by insufficient production of thyroid hormones, leading to a wide range of metabolic, physiological and psychological disturbances. There is no direct description of hypothyroidism in Ayurveda but based on its clinical presentation hypothyroidism can be correlated with Galaganda. In ayurveda, Galaganda occurs when there is vitiation of kapha and Vata doshas, predominantly Kapha which further results in a disturbance of Meda and Majja dhatus, resulting in the formation of Galaganda. The thyroid gland is situated in Urdhwajatrugata Sthana, which is a Kapha Sthana, for elimination of Kapha, Shirovirechana has been described by Acharyas. Hence the management of hypothyroidism by Nasya may be a better choice. Nasya has a direct influence on the functioning of the thyroid gland. Hence in the current study, it is proposed to evaluation of both Shodhana – Nasya with Katutumbi Taila and Shamana- Rasapachaka yoga in comparision with standard control in the management of Hypothyroidism. This study focus on early screening and assessment of  hypothyroidism through T3, T4,TSH, LIPID PROFILE and Billewicz diagnostic index and Zulewski clinical score as well as management of hypothyroidism through Nasya followed by Rasapachaka yoga. Katutumbi taila and Rasapachaka yoga preparation will be done. Pharmacological evaluation and standardization through GCMS, LCMS and  HPTLC. In trial group Nasya will be done for 7 days followed by Rasapachaka yoga given in dosage of 2 gm BD for 23 days, this cycle will be repeat in next month while in control group Tablet Thyrox given in morning at empty stomach.