Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO

The dysregulation of epidermal growth factor receptors and hormonal receptors in breast cancer can be attributed to various factors, including the influence 

of non-coding RNAs, particularly microRNAs. 

These small RNA molecules play a pivotal role in post-

transcriptional gene regulation and have been implicated 

as key players in breast cancer pathogenesis. In breast cancer, aberrant expression of miRNAs has been 

observed, with many miRNAs found to be upregulated. These dysregulated miRNAs exert their influence by 

modulating DNA repair activity and tumor suppressor 

functions, thereby promoting cancer initiation and 

progression and contributes to the molecular complexity 

of breast cancer.

in the progression of breast cancer, elucidating their 

influence on molecular markers, tumor suppressor genes, and DNA repair activity within breast cancer patient 

samples. By analyzing a panel of miRNAs in these 

patients, we seek to uncover potential biomarkers crucial 

for diagnosing breast cancer early and distinguishing 

between different subsets of the disease within a single 

comprehensive study.