Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia encountered in clinical practice and is associated with significant morbidity and mortality. Understanding AF’s clinical and epidemiological profile is crucial for effective management and risk stratification. This study aims to investigate the prevalence, symptomatology, etiological factors, and treatment outcomes of AF in a tertiary care hospital in Central India.

Material and Methods: A cross-sectional study will be conducted at a tertiary care hospital in Central India over two years. Seventy-five patients diagnosed with AF will be recruited, and demographic data, symptom profiles, etiological factors, and treatment outcomes will be systematically documented. Statistical analysis, including descriptive, bivariate, and multivariate analyses, will be performed to examine associations and trends in the data.

Expected Outcome: The study is anticipated to provide valuable insights into the clinical and epidemiological profile of AF in the study population. The findings are expected to elucidate the prevalence and distribution of AF, characterize symptom profiles, identify underlying etiological factors, and evaluate treatment responses. Additionally, the study aims to assess risk stratification using the CHADS2-VASc score and analyze secondary outcomes such as mortality, heart failure admissions, and recurrence rates. The outcomes of this study will contribute to evidence-based decision-making and improve the management of AF in clinical practice.

Keywords: Atrial fibrillation, clinical profile, epidemiology, prevalence, symptomatology, etiology, treatment outcomes, CHADS2-VASc score, Central India.