Menopause means permanent cessation of menstruation at the end of reproductive life due to loss of ovarian follicular activity. Perimenopause is the part of the climacteric where the menstrual cycle is likely to be irregular  It is associated with erratic fluctuation in reproductive hormone levels often leading to vasomotor symptoms change in mood or cognition and sexual dysfunction The prevalence of peri menopausal syndrome is 1.79% in 40 to 45 years 7.98% in 45-50 years In Ayurveda the time of Rajonivrutti is said to be 50 years  The stage of Parihani (from 41 to 70 years) which comes under classification of age according to Sushrutha can be considered as perimenopausal age During this phase Sapthadhatu starts to debilitate This is the stepping stage from Madhyama Avastha to Vruddha Avastha  This phase is the transition from Pitta Pradhana Avastha to the Vata Pradhana Avastha Both Shareerika and Maanasika doshas are affected producing symptoms like Alasya Shrama Dourbalya (physical exhaustion)  Nidranasha (sleep problems)  Klama The hormone replacement therapy is indicated in the menopausal women to overcome the short term and long term consequences of estrogen deficiency  But estrogen hormone in long term usage causes endometrial and breast cancer coronary heart disease  venous thromboembolic disease  dementia and Alzheimer disease So non hormonal way of approach through ayurveda can be a priority  Hence the study to evaluate the effect of Saptavimshati Guggulu and Soubhagya Vati after Virechana to manage both Shareerika and Manasika doshic vitiation in perimenopausal syndrome will be undertaken