1. What data in particular will be shared?
   Response - Individual participant data that underlie the results reported in this article, after de-identification (text, tables, figures, and appendices).
   


2. What additional supporting information will be shared?
   Response - Clinical Study Report
   
   
3. Who will be able to view these files?
   Response - Researchers whose proposed use of the data has been approved by an independent review committee identified for this purpose.
   


4. For what types of analyses will this data be available?
   Response - For individual participant data meta-analysis.
   


5. By what mechanism will data be made available?
   Response - Proposals should be directed to [shruti.niraj@smsimsr.org].
   


6. For how long will this data be available start date provided 28-02-2025 and end date provided 28-02-2028?
   Response - Beginning 9 months and ending 36 months following article publication.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - NIL

Background: Health Care Professionals (HCPs) experience substantial stress, anxiety and burnout, with recently reported burnout rates of 60% to 70%. The World Health Organization (WHO) defines burnout as an occupational phenomenon resulting from chronic workplace stress that has not been successfully managed. Several randomized clinical trials have evaluated strategies to reduce stress and burnout, such as the use of psychological or sensory-emotional techniques, group discussions, mindfulness or compassion-based programs, auricular acupressure, and cannabidiol treatment. These studies reported short-term improvements; however, small cohorts, high attrition rates, lack of sample diversity, or the need for pharmacological therapy have limited their utility, highlighting the need for rigorously tested interventions for burnout, anxiety, and stress.¹

Transcendental Meditation (TM) is an evidence-based meditation practice in which individuals silently recite a single mantra (a sound that lacks meaning) without concentration or contemplation. Studies on TM practitioners have revealed patterns of increased parasympathetic response leading to attenuation of the stress response. Clinical trials have demonstrated that the efficacy of TM for the reduction of stress and burnout among teachers³ and emergency department clinicians⁴. The practice of TM has been found to reduce post-traumatic stress disorder symptoms in veterans ^5,6, which might be particularly relevant because recent reports of HCW burnout suggest a similarity to the experiences of combat veterans.⁷

Aims/Objectives: The primary aim of the study is to evaluate whether engaging in TM intervention is feasible and acceptable for HCPs. The secondary aims are to assess change in measures of wellbeing, burnout, anxiety and stress at baseline, at 1-month and at 3-month follow-up.

Methodology: This is an open-label, prospective, randomized, controlled, single-centered study based in a tertiary care hospital in Rural India. Healthcare professionals will be randomized using stratified randomization based on age (<40 years vs ≥40 years), gender (male vs female) and medical profession (doctors vs nurses) into study groups A & B. Group A will receive Transcendental Meditation and group B will act as control who will have access to wellness resources. The study will assess whether engaging in TM intervention is feasible and acceptable for HCPs measured by self-report questionnaires. Validated and reliable outcome measures of wellbeing, burnout, anxiety, and stress will be collected at baseline and at 3-month follow-up.