Dentinal hypersensitivity (DH) is characterized by brief, sharp pain from exposed dentin due to external stimuli, not linked to other dental issues. It often affects the cervical areas of premolars and canines, causing discomfort that can hinder proper oral hygiene. DH is triggered by thermal, chemical, and mechanical factors such as acidic foods, toothbrush abrasion, and cold stimuli.

Exposure of dentin can result from attrition, mastication, erosion, abfractions, gingival recession, and improper brushing. Treating DH involves occluding exposed dentinal tubules, achieved through various methods including physical and chemical tubule occlusion, nerve desensitization, and photo biomodulation.

Iontophoresis is a non-invasive technique using an electric field to enhance local and systemic drug delivery in dentistry, facilitating the penetration of drugs like fluoride and lidocaine into enamel, dentin, and oral tissues. This method leverages a low current to drive ionized drugs directly to targeted areas without systemic side effects.

Biomin, an inorganic biocompatible glass compound, contains calcium, fluoride, phosphate, and silica, promoting fluorapatite formation and effective dentinal tubule occlusion. Studies highlight its superior efficacy compared to other treatments for reducing DH. The market offers various options, including SLS-free toothpastes like perfora, which provide a gentler alternative for sensitive teeth.

This study aims to compare the effectiveness of iontophoresis alone and in combination with Biomin and perfora toothpastes in managing DH, focusing on their ability to alleviate symptoms and promote oral health.