1. What data in particular will be shared?
   Response - Individual participant data that underlie the results reported in this article, after de-identification (text, tables, figures, and appendices).
   


2. What additional supporting information will be shared?
   Response -  Study Protocol
   Response -  Statistical Analysis Plan
   Response - Informed Consent Form
   Response - Clinical Study Report
   Response -  Analytic Code
   
   
3. Who will be able to view these files?
   Response - Researchers who provide a methodologically sound proposal.
   


4. For what types of analyses will this data be available?
   Response - To achieve aims in the approved proposal.
   


5. By what mechanism will data be made available?
   Response - Proposals should be directed to [drsuryanagupta@gmail.com].
   


6. For how long will this data be available start date provided 18-10-2025 and end date provided 18-06-2024?
   Response - Immediately following publication. No end date.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - NIL

Protecting and improving the health of children is of fundamental importance. One of the major illnesses in children are diseases related to the skin, skin being thin, tender, more delicate and easily susceptible to infections, it can range from mild and self- limiting conditions to more serious and chronic disorders affecting mind and other systems of the body. Living with a visible skin condition affects a child’s social and mental wellbeing, in turn affecting his/her growth in all dimensions. One of the common emerging skin disorders in children is Superficial Fungal Dermatophytosis. The prevalence of superficial fungal dermatophytosis has been increasingly growing at a rapid rate over the past few decades in industrialized and developing countries including India especially in younger children due to predisposing factors like warm, humid climate, crowded living conditions, hygiene and poor nutrition. This is probably due to the result of increase in number of immunocompromised children and sedentary lifestyle. 

In Ayurveda skin diseases are explained under the heading of Kushta, Kshudra Rogas, Visarpa, etc. and Pama is a skin disease classified under Kshudra Kushta. It is Kapha Pitta predominant and is characterized by Sweta, Aruna, Syava Pitikas, Srava, Kandu, Toda and Daha. 

Hence, based on the signs & symptoms, Superficial Fungal Dermatophytosis is analogous to Pama which occur in mild, moderate and aggravated forms.

The treatment modality for superficial fungal dermatophytosis comprises of topical application of antifungal ointments, creams, and lotions; topical steroid applications, anti-histamines and moisturizers, which makes skin sensitive on regular usage and leads to flaring up of symptoms on discontinuation of treatment. Taking antifungal medicines for an extended period or failing to complete the prescribed treatment may lead to antifungal resistance making them even more difficult to treat.

Since Pama is Kapha-Pitta Pradhana Vyadhi, Chikitsa should be basically aimed at Sthanika Nirharana of Dushta Kapha and Pitta to alleviate Pidakas, Kandu etc. Very few formulations with such properties are mentioned in the classics for the treatment of Pama, some of them being evaluated for their efficacy, but the efficacy of Pamahara Yogas with special reference to superficial fungal dermatophytosis in children are never attempted so far. As such very few Ayurvedic antifungal creams are available in the market which are proven to be safe and effective with respect to childhood Dermatophytosis. The current study is the first of its kind to evaluate the efficacy and safety of Ayurvedic Pamahara Yogas mentioned in Balarogaadhikara for their antifungal activity in children.

The study aims at providing cost-effective remedy in management of Pama Kushta in children with negligible side-effects and low recurrence rate and hence, here arises the importance of unique formulations like Grihadhoomadi Ointment and Dineshavalyadi Taila where all the drugs are Kaphapittahara and Pamahara possessing Antibacterial, Anti-inflammatory, Anti-allergic and Antimicrobial Activities. Hence, this study is an attempt to evaluate the efficacy of GRIHADHOOMADI OINTMENT and DINESHAVALYADI TAILA in the management of Pama with special reference to Superficial Fungal Dermatophytosis in children.