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CTRI Number  CTRI/2025/06/088706 [Registered on: 12/06/2025] Trial Registered Prospectively
Last Modified On: 11/06/2025
Post Graduate Thesis  No 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   Proprioceptive Neuromuscular Facilitation vs. Core Strengthening Exercises in Addressing Lower Cross Syndrome in College Students: An Experimental Study  
Scientific Title of Study   Comparison of Proprioceptive Neuromuscular facilitation strengthening and core strengthening exercises in lower cross syndrome An experimental Study.  
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Sumera Khan 
Designation  Assistant Professor 
Affiliation  Galgotias University 
Address  Department of Physiotherapy, School of Allied Health Science, Galgotias University Plot No. 2, Yamuna Expy, opposite Buddha International Circuit, Sector 17A, Greater Noida, Uttar Pradesh 203201

Gautam Buddha Nagar
UTTAR PRADESH
203201
India 
Phone  7827777195  
Fax    
Email  sumera.khan@galgotiasuniversity.edu.in  
 
Details of Contact Person
Scientific Query
 
Name  Dr Sumera Khan 
Designation  Assistant Professor  
Affiliation  Galgotias University 
Address  Department of Physiotherapy, School of Allied Health Science, Galgotias University Plot No. 2, Yamuna Expy, opposite Buddha International Circuit, Sector 17A, Greater Noida, Uttar Pradesh 203201

Gautam Buddha Nagar
UTTAR PRADESH
203201
India 
Phone  78277 77195  
Fax    
Email  sumera.khan@galgotiasuniversity.edu.in  
 
Details of Contact Person
Public Query
 
Name  Neha Sharma 
Designation  Student 
Affiliation  Galgotias University 
Address  B512 A Plot No. 2, Yamuna Expy, opposite Buddha International Circuit, Sector 17A, Greater Noida, Uttar Pradesh 203201

Gautam Buddha Nagar
UTTAR PRADESH
203201
India 
Phone  9667426507  
Fax    
Email  neha200701@gmail.com  
 
Source of Monetary or Material Support  
Research and Development Cell, Galgotias University, Plot No. 2, Yamuna Expy, opposite Buddha International Circuit, Sector 17A, Greater Noida, Uttar Pradesh, 203201 
 
Primary Sponsor  
Name  Galgotias University 
Address  Plot No. 2, Yamuna Expy, opposite Buddha International Circuit, Sector 17A, Greater Noida, Uttar Pradesh 203201 
Type of Sponsor  Research institution 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
DrSumera Khan  Department Of Physiotherapy  Room No.E003 Physiotherapy OPD Department of Physiotherapy School of Allied Health Sciences Galgotias Univesity Plot No. 2 Yamuna Expy opposite Buddha International Circuit Sector 17A Greater Noida Uttar Pradesh 203201
Gautam Buddha Nagar
UTTAR PRADESH 
07827777195

sumera.khan@galgotiasuniversity.edu.in 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Departmental Research Committee, Galgotias University  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: M00-M99||Diseases of the musculoskeletal system and connective tissue,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  Core Strengthening Exercises  • Core Stabilization Exercises: These include planks, bridges, and bird-dog exercises to activate the deep core muscles. • Dynamic Core Exercises: Progressively challenging exercises such as leg raises, mountain climbers, and side planks. • Frequency: Exercises will be performed 3 times per week for 12 weeks. • Duration: Each session will last 45-60 minutes.  
Intervention  PNF Strengthening Exercises  • PNF Stretching: Hip flexor and hamstring stretches using the contract-relax technique. • PNF Strengthening: Strengthening exercises for the abdominal and gluteal muscles using the hold-relax and repeated contraction methods. • Frequency: Exercises will be performed 3 times per week for 12 weeks. • Duration: Each session will last 45-60 minutes.  
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  25.00 Year(s)
Gender  Both 
Details  Diagnosed with Lower Cross Syndrome as confirmed by physical examination and postural assessment.
Experiencing mild to moderate lower back pain or postural issues for at least 3 months.
 
 
ExclusionCriteria 
Details  Students who have undergone any previous physiotherapy or exercise interventions for LCS in the past 6 months.
Individuals with other musculoskeletal or neurological disorders affecting posture or movement 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
Visual Analog Scale   6 week 
 
Secondary Outcome  
Outcome  TimePoints 
Functional Movement Screen   6 week 
 
Target Sample Size   Total Sample Size="60"
Sample Size from India="60" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   27/06/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="0"
Months="1"
Days="15" 
Recruitment Status of Trial (Global)   Not Yet Recruiting 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

Lower Crossed Syndrome (LCS), also known as distal or pelvic crossed syndrome, is a "S" shaped posture of the lower back that is characterized by tight hip flexors and lower back muscles associated with weak abdominal and gluteus maximus muscles. Tightness in the rectus femoris and iliopsoas crosses with tightness in the dorsal side thoraco-lumbar extensors in LCS. The gluteus maximus and medius are weak, and their weakness ventrally crosses over into the weakness of the deep abdominal muscles. Particularly in the L4-L5 and L5-S1 segments, SI joint, and hip joint, this pattern of imbalance results in joint dysfunction.(Das et al., 2017).

People who lead sedentary lives, such as office workers and sports, are more likely to acquire the illness because it is caused by repetitive or persistently bad postural habits, such as extended sitting, poor ergonomics, or activities involving constant lumbar flexion.

Due to compensatory patterns in movement brought on by muscle imbalances linked to LCS, lumbar curvature increases as muscular strength, flexibility, and mobility decrease. This causes people to frequently have severe postural instability, decreased range of Low back pain is a universal problem and lower crossed syndrome is one of the threatening combinations of biomechanical muscle imbalance due to excessive stress it places on the structures of lower back. People with such postural imbalance frequently complain of lower back pain and if it is left unchecked, this postural imbalance can generate a chronic pain condition of lower back that becomes more difficult to correct in later stages (Das et al., 2017).

 
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