| CTRI Number |
CTRI/2025/02/081173 [Registered on: 24/02/2025] Trial Registered Prospectively |
| Last Modified On: |
16/09/2025 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Observational |
|
Type of Study
|
Cross Sectional Study |
| Study Design |
Other |
|
Public Title of Study
|
Etiopathogenesis of Adenoid Hypertrophy in Ayurvedic aspect |
|
Scientific Title of Study
|
An Observational Study to Assess the Etiopathogenesis of Adenoid Hypertrophy in Ayurveda |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr SARANYA P |
| Designation |
PG scholar |
| Affiliation |
Government Ayurveda College ,Pariyaram,Kannur, Kerala |
| Address |
Department of Roganidana
Government Ayurveda College
Pariyaram
Kannur
Kerala
India
Kannur KERALA 670503 India |
| Phone |
9539824064 |
| Fax |
|
| Email |
saranyac927@gmail.com |
|
Details of Contact Person Scientific Query
|
| Name |
Dr FARSEENA K |
| Designation |
Assistant Professor |
| Affiliation |
Government Ayurveda College, Pariyaram,Kannur |
| Address |
Department of Roganidana
Government Ayurveda College
Pariyaram
Kannur
Kerala
Kannur KERALA 670503 India |
| Phone |
9995744141 |
| Fax |
|
| Email |
drfarziaman@gmail.com |
|
Details of Contact Person Public Query
|
| Name |
Dr SARANYA P |
| Designation |
PG scholar |
| Affiliation |
Government Ayurveda College ,Pariyaram,Kannur |
| Address |
Department of Roganidana
Government Ayurveda College
Pariyaram
Kannur
Kerala
Kannur KERALA 670503 India |
| Phone |
9539824064 |
| Fax |
|
| Email |
saranyac927@gmail.com |
|
|
Source of Monetary or Material Support
|
| Government Ayurveda College, Pariyaram,Kannur, Kerala, India PIN-670503 |
|
|
Primary Sponsor
|
| Name |
Government Ayurveda College,Kannur |
| Address |
Pariyaram
Kannur
670503
Kerala |
| Type of Sponsor |
Other [Government Ayurveda College] |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| Dr Saranya P |
Government Ayurveda College Hospital,Kannur |
Roga nidana department
Room number-7 Kannur KERALA |
9539824064
saranyac927@gmail.com |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| Institutional Ethics Committee-Government Ayurveda College,Kannur |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition:J352||Hypertrophy of adenoids. Ayurveda Condition: KANTHAGATAROGAH, |
|
|
Intervention / Comparator Agent
|
| sno | Intervention/Comparator | Type | Drug-Type | Procedure Name | Details |
|
|
|
Inclusion Criteria
|
| Age From |
5.00 Year(s) |
| Age To |
12.00 Year(s) |
| Gender |
Both |
| Details |
Diagnosed cases of children with Adenoid Hypertrophy aged between 5-12 years of both gender attending OPD and IPD of Government Ayurveda College, Kannur |
|
| ExclusionCriteria |
| Details |
Children with serious systemic diseases
Children taking medicines for Asthma
Children with Epistaxis
Children with serious Psychiatric illness
|
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| To propose a possible Samprapthi of Adenoid Hypertrophy |
18 Months |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Assesment of nidana,dosha,dhatu,agni,prakruthi in patients with Adenoid Hypertrophy |
18 months |
|
|
Target Sample Size
|
Total Sample Size="86" Sample Size from India="86"
Final Enrollment numbers achieved (Total)= "86"
Final Enrollment numbers achieved (India)="86" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
05/03/2025 |
| Date of Study Completion (India) |
23/06/2025 |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Date Missing |
|
Estimated Duration of Trial
|
Years="1" Months="0" Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Completed |
Publication Details
Modification(s)
|
AYURVEDIC MANAGEMENT OF PALMOPLANTAR PSORIASIS:AN EVIDENCE BASED CASE
REPORT
Saranya P1*, PM Madhu2, Farseena K2
*
1PG Scholar, 2Assistant Professor, Department of Roganidana, Government Ayurveda College, Kannur, Kerala
International Journal of Ayurveda
and Pharma Research
https://doi.org/10.47070/ijapr.v13i5.3728 |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
Brief Summary
Modification(s)
|
The study entitled “An observational study to assess the
etiopathogenesis of Adenoid Hypertrophy in Ayurveda” was conducted to analyse
the nidana, dosha, dhathu, srothas, and agni involved in the
pathogenesis of the disease. Adenoid Hypertrophy is a condition characterised
by the abnormal enlargement of the adenoid tissue, located in the nasopharynx,
which can lead to nasal obstruction, mouth breathing, snoring, recurrent
infections, and other complications. The prevalence of the disease is
increasing, and the complications that arise due to the condition are also
wide-ranging. Hence, there is a need to analyse the pathophysiology in
Ayurvedic standards to study the disease completely, as samprapthi vighatana
is chikitsa.
A total of 86 clinically diagnosed cases of Adenoid Hypertrophy
were included in the study. Data collection was done using a structured
proforma which included demographic details, family history, clinical features
observed in the patients, vital data and specific Ayurvedic assessments. The
Ayurvedic parameters studied included Prakruthi assessment, assessment
of nidanas, agni status,dosha dusthti lakshanas, dhathu involvement, and srothodusthi.
Statistical analysis was carried out using descriptive methods.
The results revealed that the majority of participants were
indulging in the consumption of kapha-vardhaka as well as agni-mandhyakara
ahara and vihara, which are considered contributory factors in
the pathogenesis of the disease. Most of the participants exhibited clinical
features suggestive of vatha-kapha pradhana dosha dushti. Among the dhathus,
mamsa dhathu and rasa dhathu were identified as the primary
factors involved in the disease causation. With regard to srothas, the
study showed the involvement of pranavaha srothas, rasavaha srothas, mamsavaha
srothas, and pureeshavaha srothas in the pathogenesis. Furthermore,
evidence of agnidushti was observed in the majority of cases, indicating
impairment in digestive and metabolic functions. Interestingly, certain Krimi
lakshanas were also traced in a considerable proportion of participants. By
analysing the above factors, a possible samprapthi of the disease was
formulated, with special emphasis on identifying and highlighting the samprapthi
ghatakas involved. |