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CTRI Number  CTRI/2025/03/082090 [Registered on: 10/03/2025] Trial Registered Prospectively
Last Modified On: 10/08/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Surgical/Anesthesia 
Study Design  Randomized, Crossover Trial 
Public Title of Study   A Comparative Study of Conventional Sniffing Position versus Left Head Rotation (LeHeR) Manoeuvre on Glottic Visualization Using Videolaryngoscope in Elective Surgery Patients Under General Anesthesia. 
Scientific Title of Study   Effect of sniffing position versus left head rotation (LeHeR) manoeuvre on glottic visualisation during videolaryngoscopy in patients undergoing elective surgery under general endotracheal anaesthesia- A prospective randomised cross-over study 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Shivani Tomar 
Designation  Junior Resident  
Affiliation  AIIMS Bathinda 
Address  Department Of Anaesthesiology, All India Institute of Medical Sciences, Bathinda.

Bathinda
PUNJAB
151001
India 
Phone  7906814086  
Fax    
Email  tomarshivani207@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Navneh Samagh 
Designation  Associate Professor 
Affiliation  AIIMS Bathinda 
Address  Department of Anaesthesiology, AIIMS Bathinda, Punjab.

Bathinda
PUNJAB
151001
India 
Phone  8427264480  
Fax    
Email  navnehsamagh@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr. Ankita Dey 
Designation  Assistant Professor 
Affiliation  AIIMS Bathinda 
Address  Department Of Anaesthesiology, AIIMS Bathinda, Bathinda,Punjab

Bathinda
PUNJAB
151001
India 
Phone  9698506683  
Fax    
Email  ankitadeyslg@gmail.com  
 
Source of Monetary or Material Support  
Department of Anaesthesiology and Critical Care, All India Institute of Medical sciences, Bathinda 
 
Primary Sponsor  
Name  NIL 
Address  NIL 
Type of Sponsor  Other [NIL] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Shivani Tomar  Department of Anaesthesiology and Critical Care, All India Institute of Medical sciences, Bathinda  Department of Anaesthesiology and Critical Care, All India Institute of Medical sciences,Jodhpur romana, Mandi dabwali road,Bathinda, Punjab -151001 Bathinda PUNJAB
Bathinda
PUNJAB 
07906814086

tomarshivani207@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Commitee  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: O||Medical and Surgical,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Arm 1-Videolaryngoscopy and intubation  Videolaryngoscopy with conventional sniffing position followed by left head rotation and Intubation with second technique. 
Intervention  Arm 2- Videolaryngoscopy and intubation  Videolaryngoscopy and Intubation with Left head rotation followed by conventional sniffing position and intubation with second technique.  
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  65.00 Year(s)
Gender  Both 
Details  BMI range of 18.5 to 35.
ASA grade I and II
Mallampati grade I,II and III  
 
ExclusionCriteria 
Details  Parturient
Thyromental distance less than six centimetres
Mouth opening less than three finger breadths
Limited head rotation
Mid-facial anomalies
Neck anomalies, cervical spine pathology
Facial fractures obstructing the airway
Known gastroesophageal reflux
Patients with a known history of coronary artery disease
Patients who are not willing to participate

 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   Sequentially numbered, sealed, opaque envelopes 
Blinding/Masking   Open Label 
Primary Outcome  
Outcome  TimePoints 
To compare the effect POGO score during sequential video laryngoscopy with conventional sniffing position versus left head rotation (LeHeR) technique in the same patient.  Intraoperatively 
 
Secondary Outcome  
Outcome  TimePoints 
To calculate the proportion of patients in each sequence in whom optimal external laryngeal manoeuvre (OELM) was needed in order to obtain a POGO score of at least 50%   Intraoperatively 
 
Target Sample Size   Total Sample Size="192"
Sample Size from India="192" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   07/11/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)
Modification(s)  
Not Yet Recruiting 
Recruitment Status of Trial (India)  Open to Recruitment 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

This thesis aims to compare the effects of the conventional sniffing position versus the left head rotation (LeHeR) manoeuvre on glottic visualization during videolaryngoscopy in patients undergoing elective surgery under general endotracheal anesthesia. The primary objective is to assess and compare the percentage of glottic opening (POGO) score between the two techniques in the same patient, while the secondary objective is to calculate the proportion of patients requiring optimal external laryngeal manipulation (OELM) to achieve a POGO score of at least 50% in each technique.

This will be a randomized, crossover study conducted over 18 months at the Department of Anaesthesia, All India Institute of Medical Sciences (AIIMS), Bathinda, Punjab. The study will involve adult patients aged 18 to 65 years, with a BMI between 18.5 and 35 kg/m², and American Society of Anaesthesiologists (ASA) physical status class I or II, who are undergoing elective surgical procedures requiring general endotracheal intubation. Patients with a variety of exclusion criteria, including significant airway or neck abnormalities, will not be included in the study. The sample size was calculated based on a non-inferiority design, with 192 patients included to account for a 10% dropout rate.

Participants will be randomly assigned to one of two groups using a computer-generated randomization sequence, with each patient undergoing both techniques in a crossover manner, ensuring a washout period between the two procedures to minimize bias. Both techniques will be performed following standard anesthetic induction, which includes the administration of midazolam, lignocaine, propofol, fentanyl, and vecuronium, with pre-oxygenation prior to videolaryngoscopy. In the sniffing position, the patient will be placed in the supine position with a pillow under the occiput to flex the neck and extend the head, while in the LeHeR technique, the patient’s head will be rotated to the left by 45°.

During each laryngoscopy sequence, the POGO score will be recorded, and if the score is less than 50%, optimal external laryngeal manipulation will be applied, with improvements in the POGO score noted. After completing both sequences, endotracheal intubation will be performed, and anesthesia will be maintained with titrated doses of propofol to maintain a Bispectral Index (BIS) between 40 and 60. Data will be collected on the POGO scores and the need for OELM, and analyzed using statistical software (SPSS, version 29) to compare the outcomes of the two techniques.

The results of this study will contribute to a better understanding of how different head positioning techniques affect glottic visualization during videolaryngoscopy and could have implications for improving airway management in clinical practice.

 
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