In ayurveda kushta is a raktapradoshaja vikara.Vicharchika is classified under kshudra kushta it is a kapha[4]/ pittapradhana tridosha kushta vikara characterized by kandu, shyava pidaka, bahusrava, daha, ruk. Though, it is Kshudra Kushtha, it runs a chronic course and has a tendency of exacerbations.

Viruddha Ahara is one potent causative factor for several diseases.Consumption of Viruddha Ahara gives rise to various disturbances of mild to violent nature and produces acute to chronic diseases. samyoga viruddha is a type of viruddha ahara formed by mixing two dravyas of balavatguna which causes vitiation of all the doshas and deha dhatus leading to manifestation of vicharchika.

Nowadays due to changing life styles, urbanization, and fascination with the western culture, there is a noticeable change in food habits and preparatory methods like mixing citrus fruits with milk ,meat and milk products.

Vicharchika is type of eczema and one of the most common skin diseases ,which affects upto 1-3% of adults in most countries of the world .The prevelence rate of eczema in India is 6.75%.

Virudha ahara taken regularly could induce inflammation at a molecular level,disturbing the eicosanoid pathway creating more arachidonic acid leading to increased PG-2 and thromboxane.This inflammatory effect is an important effect as these are all the basic pathologies that create agni mandya ,ama at 

molecular level.

It must be studied that weather such type of samyoga viruddha diet would accelerate antigen and antibody reaction and exhibit an impact on WBC.

These types of studies would also suggest that regular consumption of viruddha ahara would also lead to immunosenescence and chronic inflammation.

DLC measures the percentage of distinct WBCs in blood which increases in response to underlying infection and inflammation and thereby provide valuable information about the immune system .ESR is a measure of inflammation due to underlying chronic disease and infections.These two hematological parameters are accessed in samyoga virudha aharajanya vicharchika.

This study helps in deciding effective pathya in treatment of patient in vicharchika

Hence there a need to evaluate in detail regarding samyoga viruddha in patients with disease of Vicharchika Kusta in order to avoid reoccurrence, reduce progress and intensity of the disease.