MATERIAL
AND METHODS:
1.
All the classical texts will be well churned to
establish the facts about Karveeradi Lepa and its application
on Dadru.
2.
Thesis
a Single Blind Clinical Trial.
3.
The
main object of the present work is to undertake a clinical study of Karveeradi
Lepa in the management of Dadru.
Pharmacognostic
study of Single ingredients and its authentication will be Selection of the Cases
For this
clinical study, patient of age group 10 year to 50 years will be randomly
selected for the study. The cases will be registered on the clinical basis and
investigation from OPD and IPD of Agadtantra, Panchakarma and Kayachikitsa department
of Uttaranchal done at PG Department of Dravyaguna of
Uttaranchal Ayurvedic Medical College and Hospital, Dehradun as per guidelines.
Uttaranchal Ayurvedic Medical
College and Hospital, Dehradun, Cases will be selected randomly for this
clinical study irrespective of Religion, Occupation, Sex etc.
A detailed
proforma will be prepared on the basis of the Ayurvedic text
and allied sciences. The patient fulfilling the inclusion and exclusion
criteria will be registered on this proforma and scoring of the different
features will be done on the assessment criteria.
Inclusion
Criteria
1.
Age
group->10yearsand<50 years
2.
Sex-Both
3.
Patients
diagnosed as having Dadru on the basis of classical symptoms-
a.
Kandu
b.
Pidika
c.
Raga
d.
Rukshata
e.
Utsanmandala
Exclusion Criteria
1.
Age-<10yearsand>50years
2.
Patient
under long standing medication
3.
Pregnant Women
4.
Lactating Women
5.
Chronicity
more than 5 years
6.
Pre-existingsk
in condition
Criteria
for With-drawl
1.
Any
Inter-current Illness
2.
Personal reason
3.
If
any side effect occurs.
CRITERIA
FOR ASSESSMENT
The results
of the therapy will be assessed on the basis of clinical signs and symptoms
mentioned in Ayurvedic classics. Functional capacity of the
patients will also assess and laboratory investigations will be repeated at the
end of the treatment.
Overall
effect of the treatment will be assessed on the basis of the criteria given as
below:
a.
CompleteRemission-100% relief
b.
MarkedImprovement-75-99% relief
c.
ModerateImprovement->50-74%relief
d.
MildImprovement->25-<49%relief
e.
NoImprovement-<25% relief
GROUPING
No Grouping
because it is a Single Blind Clinical Trial.
Period– One Month
Dosing–External Application
Scoring Criteria
The result
of the therapies will be assessed on symptoms of Dadru mentioned
in Ayurveda.
|
S.
No.
|
Symptoms
|
0
|
1
|
2
|
|
1.
|
Kandu(Itching)
|
No Kandu
|
Mild (No
disturbance while doing work)
|
Moderate
(Disturbs the work)
|
|
2.
|
Raga(Erythema)
|
Normal Skin
|
Mild Redness
|
Moderate Red
|
|
|
|
Colour
|
|
|
|
3.
|
Pidika(Eruption)
|
No pidika
|
Alpa pidika
|
Madhyama pidika
|
|
4.
|
Rukshata
(Dryness)
|
No rukshata
|
Mild rukshata
|
Moderate rukshata
|
|
5.
|
Utsannamandala
(Elevation
of Lesion)
|
No Mandala
|
Mild Mandala
|
Moderate Mandala
|
Follow-Up:
• 1stFollowup–
After15th day of 2nd Sitting
• 2ndFollowUp-
After 1 month of 2nd Sitting
Method
of Data Collection:
After the
completion of treatment, the assessment will be done on same criteria as before
the treatment and scoring will be done on the same pattern. The different
tables of scores, obtained before treatment and after treatment, will be
prepared for the comparison and statistical analysis will be done.
OBSERVATION:
The
observation of the patients will be carried out before and after completion of
the treatment.
Statistical Analysis
To obtain
the efficacy of the therapy, proper statistical analysis will be carried out of
available data.
Wilcoxon
Test.
Result: The result will be analyzed
statistically and discussed.
|