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CTRI Number  CTRI/2025/01/079602 [Registered on: 27/01/2025] Trial Registered Prospectively
Last Modified On: 02/03/2026
Post Graduate Thesis  No 
Type of Trial  Observational 
Type of Study   Cohort Study 
Study Design  Other 
Public Title of Study   The management and outcomes of Femur fractures around the world 
Scientific Title of Study   Fracture Evaluation Management & Understanding Research (FEMUR): A prospective global cohort study 
Trial Acronym   
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Bobby John 
Designation  Professor 
Affiliation  Christian Medical College & Hospital Ludhiana 
Address  Department of Orthopaedics, Christian Medical College &Hospital Ludhiana, Brown Road, Punjab 141008

Ludhiana
PUNJAB
141008
India 
Phone  9815333601  
Fax    
Email  bobby.john@cmcludhiana.in   
 
Details of Contact Person
Scientific Query
 
Name  Dr Bobby John 
Designation  Professor 
Affiliation  Christian Medical College & Hospital Ludhiana 
Address  Department of Orthopaedics, Christian Medical College &Hospital Ludhiana, Brown Road, Punjab 141008


PUNJAB
141008
India 
Phone  9815333601  
Fax    
Email  bobby.john@cmcludhiana.in   
 
Details of Contact Person
Public Query
 
Name  Dr Abhishek Samuel  
Designation  Associate Professor  
Affiliation  Christian Medical College & Hospital Ludhiana 
Address  Department of Orthopaedics, Christian Medical College &Hospital Ludhiana, Brown Road, Punjab 141008

Ludhiana
PUNJAB
141008
India 
Phone  9888391208  
Fax    
Email  abhisheksamuel24@gmail.com  
 
Source of Monetary or Material Support  
Non Funded Study The study in India is coordinated by: Department Of Orthopaedics And the India Hub, NIHR Health Research Unit on Global Surgery Christian Medical College, Ludhiana, Punjab, 141008 India 
 
Primary Sponsor  
Name  University of Birmingham  
Address  Murray Learning Centre, University of Birmingham, Edgbaston, Birmingham, B152TT, United Kingdom, researchgovernance@contacts.bham.ac.uk 
Type of Sponsor  Research institution 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     Afghanistan
Albania
Australia
Belgium
Benin
Bosnia and Herzegovina
Brazil
Bulgaria
Burundi
Cameroon
Canada
Chile
Colombia
Croatia
Cyprus
Democratic Republic of the Congo
Denmark
Djibouti
Ethiopia
France
Germany
Ghana
Greece
Haiti
Hong Kong
India
Indonesia
Iran (Islamic Republic of)
Ireland
Israel
Italy
Jordan
Kazakhstan
Kenya
Lesotho
Liberia
Macedonia
Malawi
Malaysia
Malta
Mexico
New Zealand
Nicaragua
Nigeria
Norway
Oman
Pakistan
Peru
Philippines
Poland
Portugal
Qatar
Republic of Korea
Romania
Russian Federation
Rwanda
Saudi Arabia
Singapore
Solomon Islands
Somalia
South Africa
Spain
Sri Lanka
Sudan
Tanzania
Turkey
Uganda
United Arab Emirates
United Kingdom
United States of America
Uruguay
Venezuela (Bolivarian Republic of)
Zambia
Zimbabwe  
Sites of Study  
No of Sites = 17  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Prateek Behera  All India Institute of Medical Sciences, Bhopal   Department of Orthopaedics, All India Institute Of Medical Sciences, Bhopal , Madhya Pradesh (462020)
Bhopal
MADHYA PRADESH 
9348068486

prateek.ortho@aiimsbhopal.edu.in  
Dr Samarth Mittal  All India Institute of Medical Sciences, New Delhi   Department of Orthopaedics, All India Institute of Medical Sciences (AIIMS), New Delhi 110029
East
DELHI 
9013562489

samarthmittal@gmail.com 
Dr Bhaskar Sarkar   All India Institute of Medical Sciences, Rishikesh   Department of Orthopaedics, All India Institute of Medical Science Rishikesh, Uttarakhand (249203)
Dehradun
UTTARANCHAL 
8872878619

drbhaskarsarkar@gmail.com  
Dr Deny Kurien Mathew  Believers Church Medical College & Hospital, Thiruvalla  Department of Orthopaedics Believers Church Medical College & Hospital, Thiruvalla, Kerala (689103)
Pathanamthitta
KERALA 
9790359369

denymathew15@gmail.com  
Dr Bobby John   Christian Medical College Hospital Ludhiana   Department of Orthopedics, Christian Medical College Hospital Ludhiana, Punjab,141008
Ludhiana
PUNJAB 
9815333601

bjohncmc@gmail.com 
Dr Schine Kale   D Y Patil Medical College & Hospital Nerul, Navi Mumbai   Department of Orthopaedics, D Y Patil Medical College & Hospital Nerul,Navi Mumbai 400706
Mumbai
MAHARASHTRA 
9821431687

sachin.kale@dypatil.edu 
Dr Anupam Mahajan  Dr B.R. Ambedkar State Institute of Medical Science, Mohali  Department of Orthopaedics, Dr B.R. Ambedkar State Institute of Medical Science, Mohali Punjab 160055
Rupnagar
PUNJAB 
9815333663

dranupammahajan@gmail.com 
Dr Sanjeev Gupta  Government Medical College, Jammu J &K  Department of Orthopaedics, Government Medical College, Jammu J &K 180001
Jammu
JAMMU & KASHMIR 
8082787906

dr.sanjeev123@gmail.com 
Dr Nitin Kimmatkar  Government Medical College, Nagpur,   Department of orthopaedics Government Medical College and Hospital, Near Hanuman Nagar, Nagpur, Maharashtra - 440003
Nagpur
MAHARASHTRA 
9823078806

kimmatkarnitin@gmail.com 
Dr Amandeep Singh Bakshi   Government Medical College, Rajindra Hospital, Patiala   Department of orhtopaedics, Government Medical College, Rajindra Hospital, Patiala
Patiala
PUNJAB 
9915745003

dramangomco@gmail.com 
Dr kirubakaran Pattabiraman  Jawaharlal Institute Of Postgraduate Medical Education And Research (JIPMER) Pudducherry  Department of Orthopaedics Jawaharlal Institute Of Postgraduate Medical Education And Research (JIPMER) Pudducherry
Pondicherry
PONDICHERRY 
9814142209

kiru2209@gmail.com 
Dr Yash Shah  PMC hospital Kamla Nehru hospital , Pune, Maharashtra  Department of Orthopaedics PMC hospital Kamla Nehru hospital , Pune, Maharashtra
Pune
MAHARASHTRA 
7822073482

dr.yashshah@gmail.com 
Dr Vishal Kumar   Postgraduate Institute of Medical Education & Research Chandigarh  Department of Orthopaedics Postgraduate Institute of Medical Education & Research Chandigarh, 160012
Chandigarh
CHANDIGARH 
7009034172

drkumarvishal@gmail.com 
Dr Amiya Bera  Raiganj Government MCH, Raiganj  Department of Orthopaedics,Raiganj Government MCH, Raiganj, West Bengal
Uttar Dinajpur
WEST BENGAL 
8016714403

dr.a.k.bera@gmail.com 
Dr Vivek Sodhai   Sancheti Institute for Orthopaedics & Rehabilitation, Pune   Sancheti Institute for Orthopaedics & Rehabilitation, Pune, Maharashtra (411005)
Pune
MAHARASHTRA 
9921241790

vivek.sodhai89@gmail.com  
Dr Krishan Kumar   SRK Hospital and Trauma Centre Pathankot  Department of orthopedics SRK Hospital and Trauma Centre Pathankot, Punjab (145001)
Gurdaspur
PUNJAB 
9216804020

drkkortho@gmail.com 
Dr Vinutha Gowda   St.Johns Medical College, Banglore  Department of Orthopaedics, St.Johns Medical College, Banglore, India 560034
Bangalore
KARNATAKA 
9535777107

vinuthabw@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 12  
Name of Committee  Approval Status 
Institute Ethics Committee, All India Institute of Medical Sciences, New Delhi  Approved 
Institutional Ethics Committee   Approved 
Institutional Ethics committee (IEC)and Biomedical and Health Research   Approved 
Institutional Ethics Committee AIIMS Bhopal  Approved 
Institutional Ethics Committee AIIMS Rishikesh   Approved 
Institutional Ethics Committee BR Ambedkar State Institute of Medical Sciences, Mohali  Approved 
Institutional Ethics Committee GMC Jammu  Approved 
Institutional Ethics Committee GMC Patiala  Approved 
Institutional Ethics Committee PGI Chandigarh   Approved 
Institutional Ethics Committee St. Johns Medical College Bangalore  Approved 
Institutional Ethics Committee, Christian Medical College & Hospital, Ludhiana, Punjab  Approved 
Sancheti Institutional Ethics Committee   Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition: M978||Periprosthetic fracture around other internal prosthetic joint,  
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  NIL  NIL 
Comparator Agent  NIL  NIL 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  90.00 Year(s)
Gender  Both 
Details  - Adult (over 18 years of age) participants of any sex who are admitted to a facility
for definitive management of a femur fracture
- Patients receiving emergency and elective procedures should be included.
- Patient management can include non-operative and/or operative treatment of
the femur fracture. 
 
ExclusionCriteria 
Details  - Minors under 18 years of age will be excluded.
- Repeat hospital admissions for the same femur fracture will be excluded 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
- To audit mortality, morbidity, and mobility outcomes 30 days after admission with
femur fractures globally
- To describe the management of femur fractures in hospitals globally 
30 day follow up  
 
Secondary Outcome  
Outcome  TimePoints 
NIL  NIL 
 
Target Sample Size   Total Sample Size="4424"
Sample Size from India="1000" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   07/02/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  01/02/2025 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)
Modification(s)  
Open to Recruitment 
Recruitment Status of Trial (India)  Open to Recruitment 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

The femur is the largest bone in the body and femur fractures are common after injuries, globally. Femur fractures are psychologically traumatic for patients, causing severe pain and disability or death if not well managed. Multiple types of femur fracture exist, with some types being associated with high mortality rates and disability than others. However, evidence also suggest that for any given type of femur fracture, outcomes vary dramatically dependent on the geographical location of the patient. Patient age, sex, delays prior to receiving management, duration of surgery, preoperative physiological state, and management received also influence outcomes.

Evidence on outcomes after femur fracture and comparisons between management strategy and geographical regions is useful for raising awareness of disparities in quality of care and for health system planning. This evidence is currently lacking from the global literature.


The aim of this study is to understand the management provided for different types of femur fractures that are admitted to hospitals globally, and the outcomes for patients with these fractures. 




1. To audit mortality, morbidity, and mobility outcomes 30 days after admission with femur fractures globally

2. To describe the management of femur fractures in hospitals globally

In comparing outcomes by management received, facility type, and global location, we will provide data to inform health system planning and utility for global advocacy. 


This is a prospective, multicentre, cohort study conducted by the FEMUR Collaborative. The Collaborative consists of an international central team, national leads, hospital leads, and data collection teams. National and hospital leads will be purposely recruited through personal invitations to colleagues, orthopedic professional associations and informal networks, the rural doctor’s association, and social media. The central team will provide support to national and hospital leads through monthly webinars and WhatsApp group chats.


 
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