FULL DETAILS (Read-only)  -> Click Here to Create PDF for Current Dataset of Trial
CTRI Number  CTRI/2025/02/080187 [Registered on: 10/02/2025] Trial Registered Prospectively
Last Modified On: 28/11/2024
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Ayurveda 
Study Design  Randomized, Parallel Group, Active Controlled Trial 
Public Title of Study   Comparative Study Of Marma And Agnikarma In The Pain Management Of Sciatica 
Scientific Title of Study   Compative Study Of Efficacy Of Marma Chikitsa And Agnikarma In The Pain Management Of Gradhrasi(Sciatica) 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Anjali Sadani 
Designation  Md Scholar Rachna Sharir 
Affiliation  Pt Khushilal Sharma Govt Auto Ayurveda College And Institute Bhopal Madhya Pradesh 
Address  Pg Department Of Rachna Sharir Pt Khushilal Sharma Govt Auto Ayurveda College And Institute Bhopal Madhya Pradesh

Bhopal
MADHYA PRADESH
462003
India 
Phone  7049270544  
Fax    
Email  anjalisadani00@gmail.com  
 
Details of Contact Person
Scientific Query  
Name  Dr Rita Marwaha 
Designation  Professor And Hod Department Of Rachna Sharir 
Affiliation  Pt Khushilal Sharma Govt.(Auto) Ayurveda College and Institute Bhopal Madhya Pradesh. 
Address  PG Department Of Rachna Sharir Pt Khushilal Sharma Govt Auto Ayurveda College And Institute Bhopal Madhya Pradesh.
Pt Khushilal Sharma Govt Auto Ayurveda College And Institute Bhopal Madhya Pradesh
Bhopal
MADHYA PRADESH
462003
India 
Phone  9425679777  
Fax    
Email  marwaharita@gmail.com  
 
Details of Contact Person
Public Query  
Name  Dr Anjali Sadani 
Designation  MD Scholar Rachna Sharir 
Affiliation  Pt Khushilal Sharma Govt Auto Ayurveda College And Institute Bhopal Madhya Pradesh 
Address  PG Department Of Rachna Sharir Pt Khushilal Sharma Govt(Auto) Ayurveda College and Institute Bhopal Madhya Pradesh

Bhopal
MADHYA PRADESH
462003
India 
Phone  7049270544  
Fax    
Email  anjalisadani00@gmail.com  
 
Source of Monetary or Material Support  
PG Department Of Rachna Sharir Pt Khushilal Sharma Govt(Auto) Ayurveda College And Institute Bhopal Madhya Pradesh 
 
Primary Sponsor  
Name  Pt Khushilal Sharma Govt Auto Ayurveda College And Institute Bhopal Madhya Pradesh 
Address  PG Department Of Rachna Sharir Pt Khushilal Sharma Govt(Auto) Ayurveda College And Institute Bhopal Madhya Pradesh 
Type of Sponsor  Government funding agency 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Anjali Sadani  Pt Khushilal Sharma Govt Auto Ayurveda College And Institute Bhopal Madhya Pradesh  PG Department Of Rachna Sharir Pt Khushilal Sharma Govt Auto Ayurveda College And Institute Bhopal Madhya Pradesh
Bhopal
MADHYA PRADESH 		 7049270544

anjalisadani00@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethical Committee Pandit Khushilal Sharma Govt Auto Ayurveda College and Institute Bhopal Madhya Pradesh  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition:G541||Lumbosacral plexus disorders. Ayurveda Condition: GRUDHRASI,  
 
Intervention / Comparator Agent  
snoIntervention/ComparatorTypeDrug-TypeProcedure NameDetails
1Intervention ArmProcedure-marmacikitsA, मर्मचिकित्सा (Procedure Reference: DR SUNIL KUMAR JOSHI, Procedure details: STIMULATION OF MARMA STHANA FOR 0.8 SEC, 15-18 TIMES, ONCE A DAY)
2Comparator ArmProcedure-agnikarma, अग्निकर्म (Procedure Reference: CHARAK AND SUSHRUTA SAMHITA, Procedure details: 4 ANGULA ABOVE GULPHA SANDHI ON POSTERIOR SIDE OF AFFECTED LEG, 15-18 BINDU OF SAMYAK DAGDHA WITH PANCHDHATU SHALAKA)
 
Inclusion Criteria  
Age From  20.00 Year(s)
Age To  60.00 Year(s)
Gender  Both 
Details  1.Patients of either sex in the age group of 20 to 60 years.
2.Clinical signs and symptoms of gradhrasi present in the classical text
3.Tenderness at the course of Sciatic Nerve.
4.Severe pain on squatting.
5. Patient willing to be registered for study. 
 
ExclusionCriteria 
Details  1.Fracture related to spine and lower limb
2.Patients who are suffering from any systemic or metabolic disorders
3.Traumatic Infective Neoplastic conditions of spine
4.Patient having Hemoglobin less then 07.00 mg/dl
5.Cardiac diseases
6.Pregnant and lactating women
7.Patient having any hematological and bleeding disorder 
 
Method of Generating Random Sequence   Coin toss, Lottery, toss of dice, shuffling cards etc 
Method of Concealment   An Open list of random numbers 
Blinding/Masking   Open Label 
Primary Outcome  
Outcome  TimePoints 
It Is Expected That At The End Of Study Scholar Will Be Able To Evaluate The Effect Of Marma Chikitsa And Agnikarma In The Pain Management Of Gradhrasi(Sciatica).  21 Days 
 
Secondary Outcome  
Outcome  TimePoints 
Marma Chikitsa Is a Non Pharmaceutical Approach To Manage Pain In Gradhrasi(Sciatica).  21 Days 
 
Target Sample Size   Total Sample Size="30"
Sample Size from India="30" 
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" 
Phase of Trial   N/A 
Date of First Enrollment (India)   10/02/2025 
Date of Study Completion (India) Applicable only for Completed/Terminated trials 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Applicable only for Completed/Terminated trials 
Estimated Duration of Trial   Years="1"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Not Yet Recruiting 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  
The prevalence of Gridhrasi (Sciatica) is notably high, impacting over 75% of the global population. This condition presents with symptoms such as Ruja, Toda, and Stambha, starting in the Sphika and extending down to the Kati-Prishtha, Janu, Urn, and Pada. Marma Chikitsa is a non-invasive and natural approach to healing that aligns with the principles of holistic well-being.
 
Close