Caffeine is the most commonly consumed stimulant worldwide and caffeinated beverages, like coffee, have been consumed for centuries. Caffeine has been extensively studied and used to improve cognitive performance, mental alertness, and energy. Caffeine possesses performance enhancing benefits including physical endurance, reduction of fatigue, and enhancing mental alertness and concentration and therefore caffeine is consumed for a variety of reasons.

The current study is planned to assess the effectiveness of caffeine granules towards the management of mood and alertness in general healthy population. A total of 80 Eligible healthy subjects in the age group of 18-60 years of both genders will be randomized into 1:1 and will be assigned to either active caffeine or placebo group of 40 subjects each based on the protocol-defined randomization procedure. The effectiveness of the active caffeine granules will be assessed through psychometric and quality of life questionnaires. The clinical data will be processed for the statistical assessment to check the effectiveness of active caffeine granules over the placebo towards the mental alertness, mood and general well-being of the study participants. The total study duration is 15 days comprising of three clinical visits including two times blood testing at the baseline and at the end of the study. Physical examination and adverse event information will be assessed at each visit.

The effectiveness of the formulation for mood enhancing, anti-stress, alertness and over-all energetic are typically assessed in terms of the management of the parameters of mood profile and quality of life during a suggested period of 2 weeks study. This is the optimal treatment duration to demonstrate the objective of achieving the safety, efficacy and over-all acceptance of formulation for long term consumption.