| CTRI Number |
CTRI/2026/02/103261 [Registered on: 06/02/2026] Trial Registered Prospectively |
| Last Modified On: |
05/02/2026 |
| Post Graduate Thesis |
Yes |
| Type of Trial |
Observational |
|
Type of Study
|
Follow Up Study |
| Study Design |
Other |
|
Public Title of Study
|
Efficacy of Lung Ultrasound in predicting duration of Mechanical Ventilation. |
|
Scientific Title of Study
|
Efficacy of Ultrasound guided Extra-Vascular Lung Water Index measurement in predicting duration of mechanical ventilation in critical care unit - A Prospective observational study |
| Trial Acronym |
NIL |
|
Secondary IDs if Any
|
| Secondary ID |
Identifier |
| NIL |
NIL |
|
|
Details of Principal Investigator or overall Trial Coordinator (multi-center study)
|
| Name |
Dr.Theyjes |
| Designation |
Post-Graduate student |
| Affiliation |
SRM Medical College Hospital and Research Center |
| Address |
Room No. 403, Department of Anesthesia, SRM Medical College Hospital and Research Centre, Potheri.
Kancheepuram
TAMIL NADU
603203
India |
| Phone |
9790445445 |
| Fax |
|
| Email |
ts0480@srmist.edu.in |
|
Details of Contact Person
Scientific Query
|
| Name |
Dr.Anand |
| Designation |
Professor |
| Affiliation |
SRM Medical College Hospital and Research Center |
| Address |
Room No.: 410, 4th floor,
Dept. of anesthesia,
SRM General Hospital,
Potheri.
Kancheepuram
TAMIL NADU
603203
India |
| Phone |
9865282288 |
| Fax |
|
| Email |
dranandkuppusamy@gmail.com |
|
Details of Contact Person
Public Query
|
| Name |
Dr.Theyjes |
| Designation |
Post-Graduate student |
| Affiliation |
SRM Medical College Hospital and Research Center |
| Address |
Room No. 403, Department of Anesthesia, SRM Medical College Hospital and Research Centre, Potheri.
Kancheepuram
TAMIL NADU
603203
India |
| Phone |
9790445445 |
| Fax |
|
| Email |
ts0480@srmist.edu.in |
|
|
Source of Monetary or Material Support
|
|
|
Primary Sponsor
|
| Name |
SRM General Hospital |
| Address |
SRM Nagar, Potheri
Kancheepuram,
Tamil Nadu,
India 603203 |
| Type of Sponsor |
Private medical college |
|
|
Details of Secondary Sponsor
|
|
|
Countries of Recruitment
|
India |
|
Sites of Study
|
| No of Sites = 1 |
| Name of Principal
Investigator |
Name of Site |
Site Address |
Phone/Fax/Email |
| DrTheyjes |
SRM Medical College Hospital and Research Centre |
Room No. 426,
Department of Critical Care Medicine, SRM Medical College Hospital and Research Centre
Kancheepuram
TAMIL NADU |
9790445445
ts0480@srmist.edu.in |
|
|
Details of Ethics Committee
|
| No of Ethics Committees= 1 |
| Name of Committee |
Approval Status |
| SRM medical college hospital and research centre-Institutional Ethics Committee |
Approved |
|
|
Regulatory Clearance Status from DCGI
|
|
|
Health Condition / Problems Studied
|
| Health Type |
Condition |
| Patients |
(1) ICD-10 Condition: J99||Respiratory disorders in diseasesclassified elsewhere, |
|
|
Intervention / Comparator Agent
|
| Type |
Name |
Details |
| Intervention |
Nil |
Nil |
| Intervention |
Nil |
Nil |
|
|
Inclusion Criteria
|
| Age From |
18.00 Year(s) |
| Age To |
65.00 Year(s) |
| Gender |
Both |
| Details |
Patients who are receiving mechanical ventilation |
|
| ExclusionCriteria |
| Details |
Existing Lung Pathology, Rib Fractures, Neurosurgery Patients, Cardiothoracic Patients |
|
|
Method of Generating Random Sequence
|
Not Applicable |
|
Method of Concealment
|
Not Applicable |
|
Blinding/Masking
|
Not Applicable |
|
Primary Outcome
|
| Outcome |
TimePoints |
| Prediction of Duration of Mechanical Ventilation |
Measure Lung Ultrasound daily till extubation or tracheostomy. |
|
|
Secondary Outcome
|
| Outcome |
TimePoints |
| Estimation of length of stay in ICU |
Till the day of discharge of the patient from the ICU. |
|
|
Target Sample Size
|
Total Sample Size="171"
Sample Size from India="171"
Final Enrollment numbers achieved (Total)= "Applicable only for Completed/Terminated trials"
Final Enrollment numbers achieved (India)="Applicable only for Completed/Terminated trials" |
|
Phase of Trial
|
N/A |
|
Date of First Enrollment (India)
|
20/02/2026 |
| Date of Study Completion (India) |
Applicable only for Completed/Terminated trials |
| Date of First Enrollment (Global) |
Date Missing |
| Date of Study Completion (Global) |
Applicable only for Completed/Terminated trials |
|
Estimated Duration of Trial
|
Years="0"
Months="6"
Days="0" |
|
Recruitment Status of Trial (Global)
|
Not Applicable |
| Recruitment Status of Trial (India) |
Not Yet Recruiting |
|
Publication Details
|
N/A |
|
Individual Participant Data (IPD) Sharing Statement
|
Will individual participant data (IPD) be shared publicly (including data dictionaries)?
Response - NO
|
|
Brief Summary
|
Extravascular lung water is the fluid in the lung situated outside its vascular compartment which is influenced by hydrostatic pressure and capillary permeability. Intravenous fluid is the mainstay of resuscitation in a critically ill patient and its overuse culminates in fluid overload manifesting in the form of EVLW. This is clinically associated with pulmonary edema. The increase in lung water content further impairs lung function which is essential for oxygenation. Studies have shown that the reduction of EVLW results in a favorable change in outcome. This study is designed to determine the EVLW and its effect on duration of mechanical ventilation in critically ill patients. |