In a quasi-experimental study including staff nurses, the assessment of nursing skill enhancement utilising a low-fidelity simulation technique to lower the risk of catheter-associated urinary tract infection (CAUTI) would be investigated. The study will concentrate on how nurses’ proficiency with procedures like urinary catheterization can be enhanced through the use of simulation training, especially with low-fidelity simulators. The study emphasised the value of simulation in improving clinical skill, boosting self-assurance, and lowering the possibility of iatrogenic consequences from procedures like catheterization. The study made clear how well low-fidelity simulation training works to boost nurses’ self-efficacy and confidence when it comes to providing nursing care for patients with urine retention. It enhanced patient safety and care quality by giving nurses a secure setting in which to frequently practise skills until mastery. It has been determined that employing simulation as a teaching method is appropriate for the nursing profession since it allows nurses to make mistakes and grow from them without worrying about endangering patients. Overall, the study will demonstrate the value of simulation in nursing education, especially when it comes to improving the clinical skills, competence, and confidence of nurses. Simulation training is essential for preparing nurses for the difficulties they may encounter in clinical settings because it provides a secure setting for repeated practice and skill improvement. This, in turn, improves patient outcomes and the quality of healthcare provided.