1. What data in particular will be shared?
   Response - All of the individual participant data collected during the trial, after de-identification.
   


2. What additional supporting information will be shared?
   Response -  Study Protocol
   
   
3. Who will be able to view these files?
   Response - Anyone
   


4. For what types of analyses will this data be available?
   Response - To achieve aims in the approved proposal.
   


5. By what mechanism will data be made available?
   Response - Proposals should be directed to [tabasumfatim281@gmail.com].
   


6. For how long will this data be available start date provided 10-07-2026 and end date provided 01-02-2050?
   Response - Immediately following publication. No end date.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - nil

Hyperlipidaemia/Dyslipidaemia (Fart e Tassamum fid dam) is a major health problem as it plays an important role in the development of coronary artery disease (CAD) and is responsible for more than four million deaths annually and also accountable for developing IHD worldwide. In Asia, the prevalence of coronary heart disease (CHD) is approximately four times higher as compared to the general population in the USA. If it is not monitored properly or left untreated, it affects overall health and could lead to catastrophic consequences like atherosclerosis, stroke, and ischemic heart disease (IHD). Studies have proved well well-established association between dyslipidemia and the development of cardiovascular diseases. In the Unani system, it is described elaborately about the ill effects of management, if fat is pathologically increased in blood. When these oily substances of blood reach different organs of the body, they start to deposit there in the form of fat (Shahm) due to BaridMizaj (Cold temperament) of those organs.Siman-eMufrit (obesity)has also been discussed extensively and managed in the Unani system of medicine (USM) for centuries. The possible consequences of obesity are Khafqan (palpitation),Salabat-e-Nabz (Atherosclerosis), Sakta (Stroke), Zeeq-un-Nafas(breathlessness), Coma, and sudden death are very much similar to the signs, symptoms and complications of dyslipidemia defined in conventional medicine. Hence, Siman-e-Mufrit is a disease in which there is a deposition of BaridRatabMad’da(Shahm/Lipid) and it falls under the category of Amraz-e-Balghamiya.In Unani classical literature Barg-e-Bed Sada has some actions, like Muqawwi-e-Dimag (Brain Tonic), Muqawwi-e-Qalb (Cardiac Tonic), Zof-e-Meda (Cardiac Asthenia), Mudir-e-Baul (Diuretic), Qabiz (Astringent). So, it is used to cure many diseases such as Tape-Haar (Acute Fever), Ramad (Acute Conjectivitis), Sara (Epilepsy), Yarqaan (Jaundic), Warm-e-Tihal (Hepatomegelly), Khafqaan (Palpitation), Jadri (Chickenpox), Ikhtinaq-i-Reham (Hysteria), Waja-ul-Mafasil (Arthritis), Niqras. Hijamah is also used for the treatment of Hyperlipidaemia. The present study was designed to compare the efficacy of regimenal therapy and pharmacotherapy and determine which was more efficacious

Study design: Open, comparative study.

Sample size: 30 patients; 15 in each group.

Intervention. Hijamah bis Shurt

Number of Cups: 2 cups on interscapular area.

Test Drug: Salix Alba

Part used:Bark

Dosage: 7 grams

Method of Prepration:Boil 7 grams of dried and powdered bark of Salix Alba in 35ml of water and strain, then taken in the morning after breakfast.

Duration and Procedure of Intervention:

The area will be selected and cleaned thoroughly with betadine, then two cups will be taken and suction will be applied with the help of a suction machine for five minutes after which cuts will be made with sterile 11 no surgical blade and the cups are applied again and suction applied again and blood is taken out till another five minutes, then the cups will be removed and will be disposed properly, the wound will be cleaned again and surgical dressing will be applied. This procedure will be done every 15 days for two months.

Duration of Study: 2 years

Procedure of study:

Enrolled cases of dyslipidaemia will be randomly allocated into two groups of 15 each, after obtaining a written informed consent. Group A will be allocated forHijamahbisShurt(Wet cupping)  and Group B will be treated with Salix Alba.

The pre and post treatment subjective and objective findings (effects) will be compared in both groups, and its significance will be evaluated through a suitable statistical test.