NEED OF STUDY:

Decreased Bone Mineral Density (BMD) is a major consequence that is associated with feeble, frail and fractured bones .[i]Osteoporosis and its worst outcomes such as fractures and chronic pain are common in both genders, however, women are more vulnerable, accounting for 70–80 percent of all traumas including hip, spine and wrist fractures[ii]. This prevalence increases further in postmenopausal women because of reduced estrogen levels resulting in accelerated loss of bone mass [iii].According to WHO, 30 % of postmenopausal women suffer from osteoporosis. Estrogen deficiency play an important role in development of osteoporosis. So we can say that  postmenopusal  women tend to loose bone      at a rapid rate compared to younger age . [iv]

According to WHO diagnostic classification of osteoporosis is defined by BMD. Many evolving clinical factors that influence the risk of osteoporotic changes are  poor exposure of sunlight, nutritional factors specially calcium deficiency, vit D deficiency, postmenopausal hormone mediated metabolic elements and low bone mineral density. The prevalence of osteoporosis is observed four time more common in women than in men.

DXA has become the most widely used method to assess bone mineral density. Important features of DXA that made it popular were easy of use, high precision, and low radiation exposure to the patient. The noninvasive measurement of bone mass in the rat using DXA has proved to be accurate and precise, and DXA has become a primary search tool for the assessment of bone mineral density in an experimental environment. These developments the have inspired a multitude of clinical studies with serial bone mineral density assessment using DXA measurements assess the efficacy of the study medication in preserving or gaining bone mass.[v]

The present study is to assess the status of Asthi Dhatu Sarata in premenopausal stage and postmenopausal stage according to Ayurvedic prespective with special reference to BMD.

AIM:

To assess the status of Asthi Dhatu Sarata in premenopausal Group in comparison to postmenopausal  group  with  special reference to Bone Mineral Density.

OBJECTIVES:

Ø  To study the physiology of Asthi Dhatu Sarata

Ø  To study the physiology of Rajah

Ø To assess the Asthi Dhatu Sarata and Bone Mineral Density in  Pre and Post Menopausal women

Ø  To compare the Bone mineral density status in  premenopusal group and post menopausal     group

HYPOTHESIS:

NULL HYPOTHESIS (H0):

There is no relation in status of Asthi Dhatu Sarata  in premenopausal group and post menopausal  group With Special Reference to Bone Mineral Density.

ALTERNATIVE HYPOTHESIS (H1):

There is relation in status of Asthi Dhatu Sarata  in premenopausal group and  postmenopausal group with special reference to Bone Mineral Density .

OUTCOME:

PRIMARY OUTCOME:

 Assessment of the Bone Mineral Density in premenopausal and postmenopausal women

SECONDARY OUTCOME:

Assessment  of the status of Asthi Dhatu  Sarata in premenopausal women and postmenopausal women