1. What data in particular will be shared?
   Response - Individual participant data that underlie the results reported in this article, after de-identification (text, tables, figures, and appendices).
   


2. What additional supporting information will be shared?
   Response -  Study Protocol
   Response -  Statistical Analysis Plan
   Response - Informed Consent Form
   
   
3. Who will be able to view these files?
   Response - Researchers whose proposed use of the data has been approved by an independent review committee identified for this purpose.
   


4. For what types of analyses will this data be available?
   Response - To achieve aims in the approved proposal.
   


5. By what mechanism will data be made available?
   Response - Proposals should be directed to [prosthorctcdcri@gmail.com].
   


6. For how long will this data be available start date provided 01-12-2027 and end date provided 31-12-2032?
   Response - Beginning 3 months and ending 5 years following article publication.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - NIL

Objectives: The purpose of this study is to compare the biological and mechanical outcomes of teeth prepared using biologically oriented preparation technique (BOPT) and restored with CAD-CAM zirconia or CAD-CAM Metal-ceramic crowns

Material and Methods: The study will be conducted as a single-center randomized clinical trial with two parallel arms. Ethical clearance will be obtained and the trial will be conducted according to the Declaration of Helsinki. Patients visiting the outpatient department of Prosthodontics will be enrolled according to the inclusion and exclusion criteria after obtaining informed/written consent. A total of 78 patients requiring single crowns in endodontically treated premolar or molar teeth will be randomized (1:1 ratio) to receive CAD-CAM Zirconia (ZIR Group) or CAD-CAM Metal Ceramic Crown (MCC Group).

       The tooth will be prepared according to the BOPT protocol and immediately restored with a temporary (provisional) crown. After 4 weeks the impressions for the permanent crowns will be made. The permanent CAD-CAM zirconia or CAD-CAM metal-ceramic crowns will be fabricated in the laboratory according to the manufacturer’s instructions. The permanent crowns will be cemented with glass ionomer cement. The outcome assessment will be done by an experienced clinician who will be blinded. The clinical performance of the crowns will be assessed using revised FDI criteria for direct and indirect restorations (2023). The definitive crowns that belong to the “sufficient category” (clinically excellent, clinically good, clinically satisfactory ) in the revised FDI criteria  (2023) will only be cemented others will be discarded and remade. Follow-up assessment will be done 1 week after the cementation of permanent crowns (baseline), at 6 months, 1 year, 2 years, and 3 years. Technical complications will be compared between the two groups and survival rate will be assessed using the Kaplan-Meir estimate after 1 and 3 years. The probing pocket depth, clinical attachment level,  plaque index (Rustogi Modification of Navy Plaque Index 1992), and bleeding on probing (Ainamo and Bay) will be measured 1 week after the cementation of permanent crowns (baseline), at 6 months, 1 year, 2 years, and 3 years and compared with the unrestored or minimally restored contralateral control tooth.