Information on the Trial procedure and Drug: In Group A Laghu Sutashekhara Rasa, 500 mg, orally with luke warm water, thrice a day after meal for 45 days along with Brihata Dashmoola taila nasya at a dose of 6-6 drops in each nostril at morning (4 sittings, each sitting of 7 days with an interval of 3 days) will be given. In Group B: Only Laghu Sutasekhara Rasa, 500 mg, orally with luke warm water, thrice a day after meal for 45 days will be given. We assure that we will prepare formulations as per S.O.P in the pharmacy of I.T.R.A.

Description of the process: In present study, participants who will be clinically diagnosed and confirmed cases of Migraine enlisted in inclusion criteria will be enrolled. All participants will be divided into two groups by computer generated randomization technique having minimum of 15 patients in one group. Group A will be given with Laghu Sutashekhara Rasa, 500 mg orally with luke warm water thrice a day after meal along with Brihata Dashmoola taila nasya (4 sittings, each sitting of 7 days with an interval of 3 days) and Group B will be given only with Laghu Sutashekhara Rasa, 500 mg orally with luke warm water thrice a day after meals, for 45 days. Follow-up: After completion of the treatment, the patient will be followed up for 1 month at an interval of 15 days. Side Effects: We will follow closely and keep track of any unwanted effects. We may use some other medicines or stop the usage of drug to decrease the symptoms of the side effects. Results: The efficacy of the therapy will be asssessed on the basis of subjective criteria. Benefits: Project will help us to resolve the research, but future generations are likely to be benefited as to find out proper treatment protocol for the management of Migraine. Collected information from this research project will be kept confidential, all outcomes will be noted in tabular form and appropriate tests will be applied to compare the effect.