It’s a â€œComparative interventional study” To compare the efficacy and side effects of stromal vascular fraction‐enriched platelet‐ rich plasma therapy versus platelet rich plasma therapy in the treatment of Androgentic Alopecia . Androgenetic alopecia is characterized by progressive patterned hair loss. AGA is hereditary and the circulating androgen hormones may cause the conversion of terminal hair to vellus by miniaturization of hairfollicles. In the treatment of androgenetic alopecia, currently minoxidil and oral finasteride, are the only two therapeutic drugs approved by the Food and Drug Administration (FDA) and European Medicines Agency (EMA). They must be used lifelong and daily, as its interruption is followed by gradual return of hair loss. They may have limited degree of improvement in some patients. 

Platelet rich plasma(PRP) has a good potential in treatment of AGA and has gained popularity since last decade. PRP contains many growth factors that can activate the proliferative phase of hair bulge area of the follicles 

Adipose tissue derived stromal vascular fraction(SVF), is an emerging treatment for AGA. It contains non cultured regenerative cells -mesenchymal cells or adipose cells that can “home” to the site of injury. The restoration of hair with PRP in AGA can be augmented by enriching PRP with SVF. 

In our study we want to know if enriching PRP with SVF gives better hair restoration in AGA as compared with PRP alone.

Each patient will undergo two sessions at an interval of 4 weeks. They will be followed up monthly for 2 months till the last session. After PRP and SVF‐PRP therapy, the improvement will be assessed using pre‐ and post‐ treatment photographs, Physicians global assessment (PhGAS) scores, Patients global assessment score(PaGAS), Alopecia quality of life assessment and trichoscan after every session. Alopecia quality of life assessment will be assessed by using dermatology life quality index(DLQI). DLQI will be performed before the start of treatment and at the end of follow up period.