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CTRI Number  CTRI/2024/06/069325 [Registered on: 20/06/2024] Trial Registered Prospectively
Last Modified On: 02/09/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Other 
Public Title of Study   Effect of video game based daily activity training on hand function and reaction time in young and middle-aged elderly: An Experimental study 
Scientific Title of Study   Effect of Activities of Daily Living simulated exergaming on hand function and reaction time in young and middle old elderly: An Experimental study 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Vidhi Hitesh Doshi 
Designation  Masters of Neurophysiotherapy Student 
Affiliation  K J Somaiya College of Physiotherapy,Sion 
Address  K J Somaiya College of Physiotherapy, Adult Neuro Rehabilitation OPD number 10, Ayurvihar, Eastern Express Highway, Sion Mumbai MAHARASHTRA 400022

Mumbai
MAHARASHTRA
400022
India 
Phone  08291706828  
Fax    
Email  vidhi.doshi@somaiya.edu  
 
Details of Contact Person
Scientific Query
 
Name  Dr Mugdha Oberoi 
Designation  Associate Professor 
Affiliation  K J Somaiya College of Physiotherapy,Sion 
Address  K J Somaiya College of Physiotherapy, Adult Neuro Rehabilitation OPD number 10, Ayurvihar, Eastern Express Highway, Sion Mumbai MAHARASHTRA 400022

Mumbai
MAHARASHTRA
400022
India 
Phone  9820585119  
Fax    
Email  mugdha@somaiya.edu  
 
Details of Contact Person
Public Query
 
Name  Dr Mugdha Oberoi 
Designation  Associate Professor 
Affiliation  K J Somaiya College of Physiotherapy,Sion 
Address  K J Somaiya College of Physiotherapy, Adult Neuro Rehabilitation OPD number 10, Ayurvihar, Eastern Express Highway, Sion Mumbai MAHARASHTRA 400022

Mumbai
MAHARASHTRA
400022
India 
Phone  9820585119  
Fax    
Email  mugdha@somaiya.edu  
 
Source of Monetary or Material Support  
NIL 
 
Primary Sponsor  
Name  K J Somaiya College of Physiotherapy, 
Address  K J Somaiya College of Physiotherapy, Adult Neuro Rehabilitation OPD number 10, Ayurvihar, Eastern Express Highway, Sion Mumbai MAHARASHTRA 400022 
Type of Sponsor  Research institution and hospital 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Vidhi Hitesh Doshi  K J Somaiya College of Physiotherapy  K J Somaiya College of Physiotherapy, Adult Neuro Rehabilitation OPD number 10, Ayurvihar, Eastern Express Highway, Sion Mumbai MAHARASHTRA 400022
Mumbai
MAHARASHTRA 
08291706828

vidhi.doshi@somaiya.edu 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee K J Somaiya College of Physiotherapy  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  Community dwelling Elderly People in age group 60-80 years 
 
Intervention / Comparator Agent  
Type  Name  Details 
Intervention  Activities of Daily Living Simulated exergaming  Elderly patients will be given Activities of Daily Living (ADL) simulation training using ADL simulated mode of Mobi L of Rymo Technologies Pvt.Ltd. company. Safety precautions will be taken throughout the treatment. The participant will be sitting on a chair. Researcher will be by the side of the patient. Height will be adjusted according to the participant and the tablet will be kept at eye level of the patient on one side at an angle of 40-45 degrees. After every game, time required to change the game will serve as a rest period which will be approximately 1 minute. Additionally, if they require a rest period in between then that will also be given. The games include: 1)House vault training using door knob and key attachments 2)Gardening using Forearm pronation and supination attachments, 3)Pack your bag: using Wrist flexion and extension attachment, 4)Stamping using Shoulder internal and external rotation attachment Each game will be given for 10 repetitions each for both hands. The intervention will be 5 sessions/week for 2 weeks Intensity will be submaximal resistance for both hands. 
Comparator Agent  Exercise which will be similar to Exergaming Group but without ADL simulation and visual feedback using Yellow Theraband  Exercises using Yellow Theraband will include Wrist flexion and extension, Forearm pronation and supination, Shoulder internal and external rotation. There will be 10 repetitions each for both the hands. The intervention will be for 5 sessions/ week for 2 weeks 
 
Inclusion Criteria  
Age From  60.00 Year(s)
Age To  80.00 Year(s)
Gender  Both 
Details  60 to 80 years community dwelling elderly able to understand and follow instructions
in English
Individuals of all genders
Individuals scoring more than 3 in Mini-Cog scale
 
 
ExclusionCriteria 
Details  1. Individuals with any uncorrected visual or auditory impairment.
2. Individuals with a history of surgical, traumatic, inflammatory musculoskeletal
condition, unstable angina or any neurological conditions or any acute upper limb
injury in the past 6 months.
3. Any hospitalisation in the past 6 months. 
 
Method of Generating Random Sequence   Computer generated randomization 
Method of Concealment   An Open list of random numbers 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
1. Minnesota Manual Dexterity test for gross motor skills
2.Purdue Pegboard test for fine motor skills
3. Duruoz Hand Index- self-reported questionnaire for assessing the hand activity limitation and its effect on ADLs
4. Deary Liewald reaction time test 
(a) Pre-treatment assessment
(b) After one week of intervention
(c) After two weeks of intervention 
 
Secondary Outcome  
Outcome  TimePoints 
NIL  NIL 
 
Target Sample Size   Total Sample Size="64"
Sample Size from India="64" 
Final Enrollment numbers achieved (Total)= "0"
Final Enrollment numbers achieved (India)="66" 
Phase of Trial   Phase 2 
Date of First Enrollment (India)   01/07/2024 
Date of Study Completion (India) 30/04/2025 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Date Missing 
Estimated Duration of Trial   Years="1"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Completed 
Publication Details
Modification(s)  
N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary
Modification(s)  

This experimental study aimed to evaluate the effect of Activities of Daily Living (ADL)-simulated exergaming on hand function and reaction time in young-old and middle-old elderly individuals.

Primary Objectives:

1. To assess hand function (gross motor, fine motor, and functional limitation) in the Exergaming group pre-intervention, after one week, and after two weeks using the Minnesota Manual Dexterity Test (MMDT), Purdue Pegboard Test (PPT), and Duruoz Hand Index (DHI).

2. To assess hand function in the control exercise group at the same three time points using the same outcome measures.

3. To assess reaction time in the Exergaming group pre-intervention, after one week, and after two weeks using the Deary–Liewald Reaction Time Test (DLRT).

4. To assess reaction time in the control group at the same three time points using the DLRT.

5. To compare hand function between the Exergaming and control groups using MMDT, PPT, and DHI.

6. To compare reaction time between the Exergaming and control groups using the DLRT.

Methods:
This experimental study included 66 participants, with 33 in the Exergaming group and 33 in the control group. The intervention lasted for two weeks, with 10 supervised sessions administered. Data were analysed using GraphPad Prism 10 Free version. The Shapiro–Wilk test assessed normality. Within-group comparisons at three time points (pre-intervention, post-1-week, post-2-weeks) were analysed with Repeated Measures ANOVA for MMDT, PPT, and DLRT. For DHI (non-parametric), the Wilcoxon matched-pairs signed-rank test was used. Between-group comparisons were analysed with One-Way ANOVA and Tukey’s post-hoc test for parametric data, and the Mann–Whitney U test for DHI. A significance level of p < 0.05 was maintained.

Results:
Both groups demonstrated improvement in hand function over the intervention period; however, participants in the Exergaming group showed significantly greater gains compared to the control group. Improvements were observed consistently across the Minnesota Manual Dexterity Test (MMDT), Purdue Pegboard Test (PPT), and Duruoz Hand Index (DHI), indicating enhanced gross and fine motor dexterity as well as better self-reported functional hand use.

In terms of reaction time, the Exergaming group exhibited significant reductions in Deary-Liewald Reaction Time (DLRT) scores for both simple and choice reaction time, reflecting faster processing speed and improved motor responsiveness. The control group also demonstrated some improvement, though to a lesser extent.

When comparing groups, the Exergaming intervention outperformed the control intervention across all primary outcome measures. Statistically significant between-group differences were observed in MMDT, PPT, DHI, and DLRT, confirming that exergaming provided superior benefits for both hand function and reaction time relative to traditional exercises.

Conclusion:
All study objectives were successfully fulfilled.

ADL-simulated exergaming was found to be a feasible and effective intervention to enhance hand function and reduce reaction time in elderly individuals, and it may be considered as a useful adjunct in geriatric rehabilitation programs.

The findings emphasize that rehabilitation strategies which integrate biological (motor function), psychological (cognitive-motivational), and social (participation, independence) domains may yield more holistic and sustainable outcomes in the elderly. ADL-simulated exergaming therefore represents not only an effective motor training tool but also a comprehensive biopsychosocial intervention that can be incorporated into geriatric rehabilitation programs to promote independence, safety, and quality of life.

 
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