CTRI

To compare the pain perception in mandibular molars with Symptomatic Irreversible Pulpitis with three techniques viz Intrapulpal Injection with Endo Ice and Ice Sticks, Intrapulpal Injection with Benzocaine Gel and Intrapulpal Injection alone: A Randomized Controlled Trial

1) To compare and evaluate the efficacy of intrapulpal injection with Endo Ice and Ice Stick, intrapulpal injection with Benzocaine Gel and intrapulpal injection alone in reducing pain perception during administration of intrapulpal injections for symptomatic irreversible pulpitis in mandibular molars.

2. 2) To evaluate the extent of pain relief achieved with each intrapulpal anesthetic technique.

30 patients with a non-contributory medical history, will be selected and divided Â· into three groups.

GROUP 2 (n = 10)- Benzocaine Gel application followed by Intrapulpal Injection

Patients diagnosed with symptomatic irreversible pulpitis will receive standard IANB injections by using 1.8ml of 2% lidocaine with 1:80,000 epinephrine for the root canal treatment. The anaesthetic solution will be administered with a 27-G, long (31-mm) needle inserted slightly laterally at the middle portion of the pterygomandibular raphe to contact bone with the needle bevel directed toward the bone, slightly withdrawn, and aspirated, and solution will be deposited over a period of 60 seconds.

After 15 minutes of IANB, each patient will be asked whether his or her ipsilateral lip and tongue are numb. If profound lip numbness is not recorded within 15 minutes, the block will be considered unsuccessful, and the patient will be excluded from the study. When the ipsilateral lip and tongue numbness appear, the involved teeth will be isolated with a rubber dam, and a conventional access opening will be initiated.

Access opening will be done into the pulpal chamber using high- and low-speed instrumentation with light and intermittent pressure to minimize the patientâ€™s discomfort.

In case of pain during access opening procedures, patientâ€™s tooth will be classified under Endodontic Emergencies During Treatment as â€œHOT TOOTHâ€ and the treatment procedure will be stopped. The patient will then be allocated to 1 of the 3 study groups using randomization method mentioned.

For GROUP 1, Endo-ice (1,1,1,2 tetrafluoroethane) will be applied for a total of 20 seconds (10 seconds on buccal and 10 seconds on lingual surface) of the affected tooth. Subsequently Ice Sticks will be placed directly in pulp chamber for 5 minutes and followed immediately by intrapulpal LA injection. Thereafter patient will be asked to rate the pain during the intrapulpal injection on HP VAS.

For GROUP 2, after deroofing the pulp chamber, anaesthetic gel (20% Benzocaine) will be applied on exposed pulp for 5 minutes followed by intrapulpal injection. Thereafter patient will be asked to rate the pain during the intrapulpal injection on HP VAS.

For GROUP 3, patient will be given intrapulpal injection alone. Thereafter patient will be asked to rate the pain during the intrapulpal injection on HP VAS.

Anesthesia will be categorized as determined to be effective when the patient could tolerate continuation of the treatment.

The working length will be confirmed using an electronic apex locator and periapical radiographs. A glide path will be established with K-files up to a size #15, and the canals will be prepared using nickel titanium rotary files. Biomechanical preparation will be done and the root canal procedure will be carried out.