Optimal space closure is a pivotal aspect of orthodontic treatment, particularly challenging in patients with bimaxillary protrusions and Angle’s Class II Division 1 malocclusion. Two primary methods, friction and frictionless mechanisms, are employed for anterior teeth retraction. However, concerns over prolonged treatment duration and increased anchorage demands have prompted exploration into non-frictional approaches. Biomechanical properties significantly influence the efficacy of retraction loops, with ideal loops exhibiting high moment-to-force (M/F) ratios and low force-to-deflection (F/D) ratios. Inspired by existing designs, the "PRP loop" was developed, showing promising biomechanical characteristics in a finite element study. However, its clinical efficacy remains unexplored. This study aims to evaluate and compare the PRP loop with the Opus loop for anterior en-masse retraction in Angle’s Class I Dewey’s Type 2 malocclusion.

Literature review reveals studies highlighting the importance of loop design on tooth movement efficiency and anchorage preservation. Methodology involves a prospective, single-blinded randomized clinical trial with 30 patients divided into PRP and Opus loop groups. Treatment procedures include initial alignment, maxillary premolar extractions, and retraction using respective loops. Evaluation criteria encompass retraction rate, efficacy, and anchorage loss measured through clinical and radiographic assessments.

Statistical analysis will employ Student’s t-test with GraphPad Prism 7.0 and SPSS 27.0 software. Results will contribute to understanding the clinical effectiveness of the PRP loop compared to the Opus loop, providing valuable insights into optimizing space closure techniques in orthodontic practice.