This study includes the sample size of between 4070 86 patients belong the age group year and history of knee pain more than 3 months hi story of patient was taken in pain clinic and they underwent . Detailed a thorough physical examination. Patient s fulfilling the criteria were explained about treatment modality in detail and informed consent was obtained & their pain sc ore by WOMAC scoring was assessed

P latelet Rich Plasma(PRP) PREPARATION : About 30 ml of patients blood was taken from vials 4.2ml of acid dextrose solution in sterile 5 ml of PRP. antecubital vein and mixed with to get about 3 and it centrifuged telet After centrifuging the concentration of pla patients blood was assessed. Procedure: in PRP and After all those initial preparation, the patient was taken to operating with proper monitoring with pulse oximeter, ECG, non invasive blood pressure through room out the procedure. Two large IV cannula was established and one unit of RL was started in one IV cannula and inj. Ondansetron 4mg IV , inj. Midazolam 1mg IV , inj. Fentanyl 25 mcg was given as antiemetic, anxiolytic, analgesic basis respectively. Patient was lies on his back , exposing slightly flexed the knee joint and the affected knee joint . Routine disinfection was done with iodophor . inj. lignocaine p 2% was infiltrated in to the skin / subcutaneous tissue. And then 3 ml of autologous PRP was administered in the patellofemoral joint space at outer edge of patella and then knee joint was slightly flexed and extended for several times to ma ke sure PRP fully cover the articular surface. After the injection patient was instructed to avoid strenuous same exercise And the procedure was done once in a week for a 3 consecutive week After the 3 shot of PRP injection in 3 consecutive week, the patients WOMAC score was assessed and it was compared with their initial WOMAC scoring.