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CTRI Number  CTRI/2024/07/070329 [Registered on: 09/07/2024] Trial Registered Prospectively
Last Modified On: 16/10/2024
Post Graduate Thesis  No 
Type of Trial  Interventional 
Type of Study   Physiotherapy (Not Including YOGA) 
Study Design  Randomized, Parallel Group Trial 
Public Title of Study   Unveiling the power of Dynamic Neuromuscular Stabilization Breathing and Buteyko Breathing 
Scientific Title of Study   Unveiling the power of Dynamic Neuromuscular Stabilization Breathing and Buteyko Breathing-A Comparative Analysis 
Trial Acronym  NIL 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  MUSKAN 
Designation  UG Student 
Affiliation  Maharishi Markendeshwar Deemed to be university mullana haryana  
Address  Exercise laboratory Room no. 2 Ground floor Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation Maharishi Markandeshwar Deemed to be University Mullana Ambala Haryana India 133207

Ambala
HARYANA
133207
India 
Phone  8437798717  
Fax    
Email  danimuskan13@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Dr Shweta Sharma 
Designation  Assistant professor 
Affiliation  Maharishi Markandeshwar Deemed to be University Mullana Ambala Haryana 
Address  Exercise laboratory Room no. 2 Ground floor Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation Maharishi Markandeshwar Deemed to be University Mullana Ambala Haryana India 133207

Ambala
HARYANA
133207
India 
Phone  8860405721  
Fax    
Email  shwetasharmampth27@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Shweta Sharma 
Designation  Assistant professor 
Affiliation  Maharishi Markandeshwar Deemed to be University Mullana Ambala Haryana 
Address  Exercise laboratory Room no. 2 Ground floor Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation Maharishi Markandeshwar Deemed to be University Mullana Ambala Haryana India 133207

Ambala
HARYANA
133207
India 
Phone  8860405721  
Fax    
Email  shwetasharmampth27@gmail.com  
 
Source of Monetary or Material Support  
Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation Maharishi Markandeshwar Deemed to be University Mullana district Ambala Haryana India 133207 
 
Primary Sponsor  
Name  Muskan 
Address  Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation Maharishi Markandeshwar Deemed to be University Mullana district Ambala Haryana India 133207 
Type of Sponsor  Other [Self] 
 
Details of Secondary Sponsor  
Name  Address 
NIL  NIL 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Shweta Sharma  Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation  Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation Maharishi Markandeshwar Deemed to be University Mullana district Ambala Haryana India 133207
Ambala
HARYANA 
8860405721

shwetasharmampth27@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethical Committee  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Healthy Human Volunteers  NA 
 
Intervention / Comparator Agent  
Type  Name  Details 
Comparator Agent  Buteyko Breathing Technique 3 days a week for 4 weeks  Buteyko Breathing Technique Duration 4 weeks Frequency 3 days a week 
Intervention  Dynamic neuromuscular stabilisation breathing 3-days a week for 4 weeks  Dynamic Neuromuscular Stabilization Breathing Duration 4 weeks Frequency 3 days a week 
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  25.00 Year(s)
Gender  Both 
Details  Healthy individuals
Patient agreement
 
 
ExclusionCriteria 
Details  Any ongoing medication
Any ongoing cardiovascular condition
Any previous surgeries 
 
Method of Generating Random Sequence   Random Number Table 
Method of Concealment   An Open list of random numbers 
Blinding/Masking   Not Applicable 
Primary Outcome  
Outcome  TimePoints 
12 minute walk test to evaluate VO2 max
 
2 time points 
 
Secondary Outcome  
Outcome  TimePoints 
Karvonen formula to evaluate Target Heart Rate  2 time points 
 
Target Sample Size   Total Sample Size="40"
Sample Size from India="40" 
Final Enrollment numbers achieved (Total)= "40"
Final Enrollment numbers achieved (India)="40" 
Phase of Trial   N/A 
Date of First Enrollment (India)   19/08/2024 
Date of Study Completion (India) 20/09/2024 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Date Missing 
Estimated Duration of Trial   Years="0"
Months="4"
Days="0" 
Recruitment Status of Trial (Global)
Modification(s)  
Not Applicable 
Recruitment Status of Trial (India)  Completed 
Publication Details   N/A 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary  

There has been a growing interest in using specific breathing techniques to enhance people’s general wellness and health in recent years. Dynamic Neuromuscular Stabilization (DNS) and Buteyko Breathing (BBT) are two of these methods that have attracted a lot of interest due to their potential benefits. These methods have shown promise in practical aspect, but it is yet unclear how they will affect well-being among individuals who are actively seeking wellness and health optimization. This study aims to bridge the current gap in knowledge and offer a thorough insight into the potential cardiorespiratory benefits linked to DNS and BBT breathing techniques. In this 4-week pilot study, a total of 40 participants will be assigned randomly to two groups: Group A received DNS and Group B practiced Buteyko breathing. The participants are selected through a random sampling method, ensuring they met specific criteria, such as age, and the absence of ongoing medication, respiratory, or cardiovascular conditions. The primary objective is to evaluate how these breathing techniques influenced cardiovascular endurance, utilizing parameters like VO2 max and target heart rate, with assessments conducted before the study, and at the and the 4-week conclusion. Each group will follow distinct breathing protocols during the 4-week training period, and a final assessment allows for comparisons within and between the groups. 

 
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