1. What data in particular will be shared?
   Response - All of the individual participant data collected during the trial, after de-identification.
   


2. What additional supporting information will be shared?
   Response -  Study Protocol
   Response -  Statistical Analysis Plan
   Response - Informed Consent Form
   Response - Clinical Study Report
   
   
3. Who will be able to view these files?
   Response - Anyone
   


4. For what types of analyses will this data be available?
   Response - Any purpose.
   


5. By what mechanism will data be made available?
   Response - Proposals should be directed to [bhagyavathis67@gmail.com].
   


6. For how long will this data be available start date provided 01-07-2024 and end date provided 01-07-2025?
   Response - Immediately following publication. No end date.
   


7. Any URL or additional information regarding plan/policy for sharing IPD? 
   Additional Information - NIL

Ayurveda is accepted as one of the oldest traditional systems of medicine worldwide. In ayurvedic classics, majority of gynaecological disorders have been discussed under Yonivyapat. Udavarta Yonivyapat is one among Vataja Yonivyapat. Due to Nidanas, the Vata Dosha gets vitiated and moved upwards, produces Raja Kruchrena Munjathi (difficult or painful menstruation) and Vedana (Generalised body aches)

Dysmenorrhea is a common menstrual complaint with major impact on women quality of life. The prevalence of dysmenorrhea varies between 16% and 91% in women of reproductive age. Dysmenorrhea means painful menstruation of sufficient magnitude so as to incapacitate day-to-day activities. Primary dysmenorrhea is where there is no pelvic pathology and is caused by psychosomatic factors (tension, stress), increased prostaglandins and vasopressin. Symptoms includes spasmodic pain in lower abdomen, nausea, vomiting, fatigue, diarrhoea, headache. The line of management includes analgesics, antispasmodics, prostaglandins synthetase inhibitors, oral contraceptives and surgery as last resort. These modalities have adverse side effects like dizziness, depression, vertigo, etc. Hence, there is a need to find safe, potent solution for dysmenorrhea.

Vamanadi Karmas like Vamana, Virechana, Anuvasana, Asthapana Basti and Nasya are mentioned as Samanya Chikitsa after proper Snehana and Swedana for all Yonivyapat. As Udavarta Yonivyapat is one among Yonivyapat, the same line of treatment can be considered. Under Panchakarma, Nasya has its action on Shiras as nose is the closest opening for conveying the potency of medicines to cranial cavity, hypothalamus secrets vasopressin and is responsible for expression of pain, stress factors. Thus, Nasya can be considered as a potential treatment modality for dysmenorrhea.

Acharya Kashyapa indicated Shatapushpa Taila Nasya in Vandyatva, which is a type of Vataja Yonivyapat and Udavarta Yonivyapat being a type of Vataja Yonivyapat, Shatapushpa Taila Nasya is considered for the study. Shatapushpa is having properties like Madhura, Balya, Brhmana, Pushti-Varna-Agni Vardhana, Rtupravartana, Yonishukra Vishodana, Ushna and Vatahara. And, Shatapushpa relives dysmenorrhea due to inhibition of prostaglandin production and antispasmodic action.