Fibroids also known as fibromyomas, myomas or leiomyomas are most common benign uterine neoplasms, derived from smooth muscle cells and fibroblasts commonly encountered in reproductive age group women.^(1,2)Approximately 30%–35% of women are diagnosed with fibroids on ultrasound, but > 70% of the women develop fibroid by the age of 50 years.^(2,3)High prevalence of uterine fibroids (UFs) has led to profound economical burden on healthcare system and it contribute to at least one-third and up to half of all hysterectomies.^(4,5) Prevalence of UFs from year 2014 to 2016 was 37.65% in rural south India (Tamil Nadu).⁽⁶⁾Most UFs are usually asymptomatic, while symptomatic patient presents with menstrual irregularity (menorrhagia followed by metrorrhagia or polymenorrhagia), abdominal pain, abdominal mass, urinary frequency, urgency and infertility. Symptoms usually depend on number, size and site of UFs.^(3,5) The size of fibroid may range from size of a tiny seedlings to as large as a melon.⁽⁶⁾ UFs are associated with impaired fertility and adverse obstetric outcomes.⁽¹⁾Treatment options for UFs in conventional medicine include analgesics, iron supplements, vitamin D3, COCs, SPRMs, gonadotropin-releasing hormone (GnRH) agonists and antagonist, drugs modulating the estrogen receptors and surgery (hysterectomy, myomectomy, uterine artery embolization (UAE), and focused ultrasound surgery (FUS), both ultrasound and magnetic resonance guided focused ultrasound surgery).^(1,7)These treatment are expensive and  are associated with lot of side effects and complications.⁽⁷⁾ Moreover, such treatment provide temporary relief from symptoms making the hysterectomy as the definitive treatment and rendering the female infertile.^(4,7,8) Thus, an alternate approach with cost effectiveness and less side effects is required.

In USM, the description of fibroid is mentioned under the heading of “sal’ah” meaning tumor, which usually consider as Waram Balghami.^(2,9) Based on the etiology of fibroid, various Unani drugs possessing the properties of anti inflammatory, anti-tumor, antioxidant and antiestrogenic effect are available which may be helpful not only to alleviate the symptoms of uterine fibroid but also to reduce its size.  Hence, a pilot study is contemplated to evaluate the efficacy of Tukhme Hulba (Trigonella foenum-graecum L./fenugreek seeds) in reducing the size of uterine fibroid.