Patient will be enrolled in the department of dermatology . History taking will be done including onset, duration and course of the disease. Clinical Examination will be done to detect association (nail changes and any other autoimmune disease) and to determine the extent of Psoriasis Vulgaris, which will be assessed using the Psoriasis Area and Severity Index (PASI) Score.

Anthropometric examination including Height, Weight, Body Mass Index(BMI), Waist circumference, Hip circumference, waist to hip ratio, will be done and baseline laboratory examinations including LFT, RFT, RBS and lipid profile consisting of cholesterol, low density lipoprotein(LDL), high density lipoprotein (HDL),Triglyceride and VLDL will be included. Blood samples will be collected after overnight fasting for analysis using (mention analyser used in biochem department)

Atherogenic Indices including Atherogenic Index of Plasma (AIP), Castelli Risk Index I and II (CRI), Atherogenic Coefficient (AC), and non-high density lipoprotein cholesterol (HDLc) (NHC)will be used to assess the risk of cardiovascular disease. These indices are calculated as:

·AIP = Log (serum triglyceride/serum HDLc).

·CRI-I = Serum total cholesterol/Serum HDLc.

·CRI-II = Serum low-density lipoprotein (LDL)cholesterol/Serum HDLc

·AC=(Serum total cholesterol-Serum HDLc)/HDLc.

·NHC=(Serum total cholesterol-Serum HDLc)

CIMT: Double-check the CIMT values on both sides to achieve reproducibility, the mean values will be generated for CIMT. The American Institute of Ultrasound in Medicine’s (AIUM) standards will serve as the foundation for the common carotid artery (CCA) sonographic protocol.

Patient’s Proforma (Annexure-I) will be filled for all the patients included in the study.