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CTRI Number  CTRI/2024/05/066992 [Registered on: 08/05/2024] Trial Registered Prospectively
Last Modified On: 21/10/2025
Post Graduate Thesis  Yes 
Type of Trial  Interventional 
Type of Study   Ayurveda 
Study Design  Single Arm Study 
Public Title of Study   Effect of Mashapinda Svedana on Muscle Wasting in Neuromuscular Disorders  
Scientific Title of Study   An observational clinical study to assess the effectiveness of Mashapinda Svedana on Muscle Wasting in Neuromuscular Disorders 
Trial Acronym  NA 
Secondary IDs if Any  
Secondary ID  Identifier 
NIL  NIL 
 
Details of Principal Investigator or overall Trial Coordinator (multi-center study)  
Name  Dr Sneha Kamleshbhai Rathod 
Designation  PG Scholar 
Affiliation  J S Ayurveda Mahavidyala & P D Patel Ayurved Hospital 
Address  Pachkarma Department of J S Ayurveda Mahavidayala College Road Nadiad

Kheda
GUJARAT
387001
India 
Phone  8320295974  
Fax    
Email  snehaayu99@gmail.com  
 
Details of Contact Person
Scientific Query
 
Name  Prof Dr Jaimin Patel 
Designation  Professor  
Affiliation  J S Ayurveda Mahavidyala & P D Patel Ayurved Hospital 
Address  Pachkarma Department of J S Ayurveda Mahavidayala College Road Nadiad

Kheda
GUJARAT
387001
India 
Phone  9427859535  
Fax    
Email  vd.jaimin@gmail.com  
 
Details of Contact Person
Public Query
 
Name  Dr Sneha Kamleshbhai Rathod 
Designation  PG Scholar 
Affiliation  J S Ayurveda Mahavidyala & P D Patel Ayurved Hospital 
Address  Pachkarma Department of J S Ayurveda Mahavidayala College Road Nadiad

Kheda
GUJARAT
387001
India 
Phone  8320295974  
Fax    
Email  snehaayu99@gmail.com  
 
Source of Monetary or Material Support  
Sundar Ayurved teaching Pharmacy of J S Ayurveda Mahavidyala & P D Patel Ayurveda Hospital, College Road, Nadiad, Gujarat 387001 
 
Primary Sponsor  
Name  J S Ayurveda Mahavidyala 
Address  Panchkarma Department of J S Ayurveda Mahavidyala College Road Nadiad 387001 
Type of Sponsor  Private medical college 
 
Details of Secondary Sponsor  
Name  Address 
Nil  Nil 
 
Countries of Recruitment     India  
Sites of Study  
No of Sites = 1  
Name of Principal Investigator  Name of Site  Site Address  Phone/Fax/Email 
Dr Sneha Kamleshbhai Rathod  P D Patel Ayurveda Hospital  J S Ayurveda Mahavidyala College Road Nadiad 387001
Kheda
GUJARAT 
8320295974

snehaayu99@gmail.com 
 
Details of Ethics Committee  
No of Ethics Committees= 1  
Name of Committee  Approval Status 
Institutional Ethics Committee MAM University Nadiad  Approved 
 
Regulatory Clearance Status from DCGI  
Status 
Not Applicable 
 
Health Condition / Problems Studied  
Health Type  Condition 
Patients  (1) ICD-10 Condition:G00-G99||Diseases of the nervous system. Ayurveda Condition: VATAVYADHIH,  
 
Intervention / Comparator Agent  
snoIntervention/ComparatorTypeDrug-TypeProcedure NameDetails
1Intervention ArmProcedure-piNDasvedaH, पिण्डस्वेदः (Procedure Reference: charaksutrasthan 14, Procedure details: Purvakarma-Abhyanga, done with Bala Taila. Then swedan with Masha Pinda gently on the body part having muscle wasting with little pressure once a day for 28 days)
(1) Medicine Name: MASHA, Reference: CHARAK, Route: Topical, Dosage Form: Churna/ Powder, Dose: 10(g), Frequency: od, Duration: 28 Days
 
Inclusion Criteria  
Age From  18.00 Year(s)
Age To  60.00 Year(s)
Gender  Both 
Details  1. Patients fulfilling th diagnostic criteria
2. Svedana Yogya persons as per Ayurvedic classics 
 
ExclusionCriteria 
Details  1. Patients having sensory loss in affected body part
2. Patients having any type of skin lesion in affected body part
3. Svedana Ayogya persons as per Ayurvedic classics
4. Known case of diseases like burn, DM, AIDS, STD, skin diseases etc. will be excluded 
 
Method of Generating Random Sequence   Not Applicable 
Method of Concealment   Not Applicable 
Blinding/Masking   Open Label 
Primary Outcome  
Outcome  TimePoints 
To observe the changes in muscle wasting, muscle power, and muscle tone before and after the Treatment  30 days 
 
Secondary Outcome  
Outcome  TimePoints 
Nil  Nil 
 
Target Sample Size   Total Sample Size="30"
Sample Size from India="30" 
Final Enrollment numbers achieved (Total)= "30"
Final Enrollment numbers achieved (India)="30" 
Phase of Trial   Phase 2/ Phase 3 
Date of First Enrollment (India)   15/05/2024 
Date of Study Completion (India) 26/06/2025 
Date of First Enrollment (Global)  Date Missing 
Date of Study Completion (Global) Date Missing 
Estimated Duration of Trial   Years="1"
Months="6"
Days="0" 
Recruitment Status of Trial (Global)   Not Applicable 
Recruitment Status of Trial (India)  Completed 
Publication Details
Modification(s)  
This will be submitted in the dissertation form 
Individual Participant Data (IPD) Sharing Statement

Will individual participant data (IPD) be shared publicly (including data dictionaries)?  

Response - NO
Brief Summary
Modification(s)  

Patients was selected from I.P.D. of PG Departments of Panchkarma and Kayachikitsa of P.D.Patel Ayurvedic Hospital, Nadiad. Detailed history was taken according to the proforma prepared for the study incorporating all the relevant points from Ayurveda as well as modern medical science.

 

Diagnostic Criteria: 

Patients already diagnosed to have neuromuscular disorders like, MND, ALS, MS, Hemiplegia, Paraplegia.

Having reduced muscle mass especially in the limbs.

 

Treatment Schedule:

 

For first 2 days --> Sarvanga abhyanga (30min) with Bala taila and Sarvanga Bashpa svedana (10min) / Nadi svedana (20min) with Nirgundipatra

For next 1 day -->   

Sarvanga Abhayanga: Bala taila

Sarvang Baspa svedana / Nadi svedana with Nirgundipatra

Mridu Virechana Karma: Erand Sneha (30-50ml) + Dindayala churna (Haritaki, Sonamukhi, Ajamoda, saindhava) (4-7gm) with Draksha kvatha according to Kostha and Bala of patient.

For next 2 days --> Samsarjana Krama

For next 1 days --> 

Sarvanga Abhayanga: Bala taila

Sarvang Baspa svedana / Nadi svedana with Nirgundipatra

Niruha Basti with Dashamula Kvatha, Madhu, Taila Taila, Putoyavanyadi Kalka and Saindhava

For next 25 days -->

Sarvanga Abhayanga (30min) with Bala taila

Sarvanga Mashapinda Svedana (30min) (Masha + cow milk + Ashvagandha Churna + Balamula Kvatha + water)

Anuvasana (Matra) Basti with Bala Taila

Shamana Chikitsa

1.Balamula Kvatha 40 ml twice, empty stomach

2.Ashvagandha Churna 3 grams twice with milk

3.Bala Taila 20-30 ml twice with warm water

 

Poorva karma:

Abhyanga was done with Bala Taila Taila for 30 min all over the body. Kept the vessel of remaining 500ml of Balamula Kvatha on mild fire to keep it warm. One of the Pinda was to be dipped in Balamula Kvatha of this vessel to keep the Pinda warm.

 

Pradhana karma (Main procedure):

Rubbing of the warm Masha Pinda was done gently on the body part having muscle wasting with little pressure. When Pinda loses its warmth, it should be replaced by warm Pinda dipped in Balamula Kvatha. Thus, Pindas should be kept warmed by repeated replacement and rubbing of the warm Masha Pinda on the body part having wasting of the muscles will be continued up to one hour. Care should be taken that the heat of the Pinda is bearable to the patient.

 

Paschat karma:

The paste of cooked Masha came out of the Pinda during rubbing should be kept on the body part for next one hour and patient is advised to sit in sun avoiding exposure to wind and cold during this period. After this, patient is advised to take shower with warm water and clean the body

The analysis was done using paired "t" test

 

 
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